JAHA

What's the prognostic significance of small left ventricle in the general population? A UK Biobank study reveals a U-shaped risk factor for MACE, especially in males. #AHAJournals ahajrnls.org/4f8DK2d

Both low and high non-HDL-C increase all-cause mortality risk. Elevated total cholesterol, LDL-C, and non-HDL-C are linked to #cardiovascular mortality. #AHAJournals ahajrnls.org/4f8XVNw

In a randomized controlled preclinical trial conducted in rodents, the molecule JM‐20 shows some neuroprotective effects in #stroke models—but less than small studies claimed. #AHAJournals ahajrnls.org/3TUDvOx

In a multicenter observational study, left ventricular enlargement ≥40mm in mitral valve prolapse with mild/moderate MR predicted worse survival; early surgery may improve outcomes. #AHAJournals ahajrnls.org/4lNe0el

In a matched Framingham cohort, TIA was not associated with higher long-term dementia risk. Post-TIA behavior and treatment changes (⬇️smoking, ⬆️anticoagulants) may mitigate risk. @hugoapariciomd @BUMedicine @FraminghamStudy ahajrnls.org/4o6UIBU

Hippocampal metabolic activity independently and incrementally predicts sudden cardiac death, partially mediated by QTc. #AHAJournals #HeartFailure ahajrnls.org/452FDIT

New systematic review of preclinical stroke studies finds that TGFβ1 improves outcomes in ischemic stroke populations, while worsening outcomes in hemorrhagic stroke. #AHAJournals @ben_hewitt97 @Dr_Bots ahajrnls.org/3TNQPnJ

Genotype-guided P2Y12 selection at time of PCI may not benefit patients on maintenance clopidogrel. #AHAJournals @UNCCardiology ahajrnls.org/4o2Z5Ow

Can cardiac biomarkers improve HF risk stratification in CKD? Yes for mortality, but not for HF hospitalizations. CKD-specific thresholds and better integration of kidney disease into HF staging are needed. #AHAJournals @loggyleila @asgmd1 ahajrnls.org/4kY8x39

Chronotropic incompetence worsens outcomes in HFpEF, predicting hospitalization and CV death. Early recognition is key. #AHAJournals #HFpEF @LinTingtse ahajrnls.org/4kY7ikv

New study suggests that 18F-FDG PET imaging identifies atrial fibrosis and low-voltage areas in persistent AF with high diagnostic accuracy. #AHAJournals @bernhard_gerber @ClinUnivStLuc ahajrnls.org/4m3N5KQ

Can AI-ECG alerts improve AF care by non-cardiologists? New cluster RCT suggests AI alerts may improve AF diagnoses and NOAC prescriptions. #AHAJournals @wtliucv ahajrnls.org/4kPTwA8

Pregnancy urinary aldosterone and potassium intake are associated with high normal child blood pressure. #AHAJournals @h_aljorani ahajrnls.org/3GBFEM4

LA stiffness outperformed conventional metrics for predicting major cardiac events in kids with HCM. #AHAJournals @NumataRyus59399 ahajrnls.org/3Iy47SZ

Major bleeding increases future CV risk, underscoring the need for tailored antiplatelet therapy in Asian ACS care. #AHAJournals @ChienYiHsu ahajrnls.org/454Ul2j

Attending #BCVS2025? Meet #AHAJournals Editors (@JAHA_AHA's Dr. Chad Grueter and Dr. Sakima Smith) & learn about publishing your work. Stop by the #AHAJournals booth on Thursday during the pm break & get your questions answered! 📅 July 24 🕔2:45-3:15pm 📍#AHAJournals booth

VZV reactivation was found in one-fifth of AIS patients who had VZV testing. HIV patients were at high risk of VZV reactivation and recurrent stroke. #AHAJournals @TyTshang ahajrnls.org/450fsTu

High education is associated with a lower risk of clinical outcomes in patients with high-risk CV disease - insights from the INVESTED trial. #AHAJournals @SheilaHegde ahajrnls.org/44ZCY2P

Mobile ICUs cut door-to-balloon time, but improved STEMI outcomes stem more from in-hospital and post-discharge care. #AHAJournals @AviadRotholz @RabinMedical_ ahajrnls.org/44ZRF67

Novel insights into the value of achieving phase-specific hemodynamic goals during percutaneous ventricular assist device (Impella) support. #AHAJournals @Kitasato_CV ahajrnls.org/3GSX4nm