Stromnes Lab
@IngunnStromnes
The laboratory of Dr. Ingunn Stromnes at the Center for Immunology, University of Minnesota-Twin Cities. Tweets by lab members.
3 groups use generative AI to design high-specificity pMHC-binding “artificial TCRs” for more precise targeting of tumor antigen @ScienceMagazine intro by @IngunnStromnes science.org/doi/10.1126/sc…
🧬 Wondering what the future holds for T cell cancer therapies? We wrote an editorial for @ScienceMagazine about how AI—like AlphaFold—is accelerating the design of T cell receptors (TCR), powering the next-generation of anti-tumor therapies. Read here! science.org/doi/10.1126/sc…
Our lab at the Center for Genome Engineering isn’t just for scientists—it’s a state resource for discovery, education, and innovation. Proud to partner with Doors Open Minneapolis to share our work with the community. 👀 Want a tour? Reach out! #GenomeEngineering #UMNResearch
📰New paper from the lab! Using our transgenic TCR model we reveal that T cell beta-selection can be bypassed via a γδ TCR alternative path that allows T cell maturation to continue. This path appears highly dependent on IL-7 signaling. Read here! academic.oup.com/immunohorizons…
We’re proud to support future scientific leaders through trainee travel scholarships! Eduardo Cruz presented his pancreatic cancer immunology research at AAI in Hawaii—and even won this awesome shirt in a conference raffle! @IngunnStromnes #GenomeEngineering #Immunology
In today’s tough budget climate, restoring funding to FY24 levels is a major win – and a direct result of thousands of advocates who have contacted Congress in support of #pancreaticcancer research funding over the past few months. 📣 This is a huge step forward – but it’s not…
We had a great time at this year's @CSHL Pancreatic Cancer Course! Ingunn gave a fantastic overview of pancreatic cancer immunology and Grant has had a weekend full of deep learning from faculty all around the country. Hope to do it again next year!

aacrjournals.org/cancerimmunolr… #GenomeEngineering #CancerResearch #Immunotherapy #UMN
We're proud to celebrate Ingunn Stromnes for her groundbreaking work in immunotherapy + genome editing. @IngunnStromnes Her latest research on engineered T cells for solid tumors is a huge step forward. Patient-focused science, powered by CGE. 👏 🔗 Below
We’re proud to celebrate Branden Moriarity, PhD who received the Angel Award from the Randy Shaver Cancer Research & Community Fund for his leadership in cancer research and innovation. Congrats! @RSCRCF @UMNCancer #CancerResearch #GenomeEngineering
Congratulations to Dr. Zoe Schmiechen on successfully defending her PhD dissertation, "Engagement of anti-tumor T cells to overcome pancreatic cancer immune evasion"!! CFI wishes her continued success as she embarks on the next exciting chapter of her career!
The shirt is super breathable too 😆
Stop by the AAI booth #523 in the Exhibit Hall for a chance to win an exclusive AAI Aloha Shirt! Today's winners will be announced at 12:30 p.m. Winners must pick up their prize by 2:00 p.m. today. Sizes are first come, first served. #AAI2025
Attending #AAI2025 and want to learn about how a new combination immunotherapy eradicates pancreatic cancer? Zoe will be giving a talk on her work investigated CD8 and CD4 T cells in a murine model of PDA as part of TIPT5 block symposium. Don't miss it!

Wow! We are crazy proud of Zoe Schmiechen for winning not 1, not 2, but three trainee awards this semester! Zoe was the recipient of the Milne/Brandenburg, J. Kaplan, and Bacaner awards. Thank you to all the committees who independently recognized Zoe's excellent research!

Hello #AAI2025 ! Want to learn about how T cell receptor strength dictates CD8 T cell funtion? Grant is presenting his research on CD8 T cell clones with varying TCR strength and how it leads to differing responses in a murine model of pancreatic cancer. See you tomorrow!

Looking forward to the #IMMUNOLOGY2025 President's Address? Join us on Saturday, May 3, with AAI President Stephen C. Jameson and distinguished guests from 16:00 – 17:15 in Ballroom BC. ow.ly/Jv4U50VLo7f.
The Stromnes lab is attending #IMMUNOLOGY2025 ! Catch Grant Hickok's talk on Saturday 10:30am in Room 311 and Zoe Schmiechen on Tuesday 7am in the TIPT5 session! @ImmunologyAAI
