Hiller Lab
@HillerLab
Group of Prof Sebastian Hiller. Structural Biology Research Group @biozentrum @Unibasel. Unravelling Biomolecular Mechanisms. (run by students)
Happy to announce the release of our collaboration with the @JenalLab! @GuillaumeMas2 led the NMR analysis, identifying the toxin’s product and unravelling the enzymatic properties of the toxin-antitoxin system.
Researchers @JenalLab and @HillerLab have discovered how a dangerous human pathogen causing pneumonia uses a kind of molecular "sleeping pill" to enter a dormant state to persist antibiotic treatment. @UniBasel_en @NCCR_AntiResist @snsf_ch @EMBOPress ow.ly/8Ro550TQrnl
Great pictures!
It was great meeting Sebastian Hiller after 18 years at the joint #APNMR-@NmrsIndia meeting at @IISERPune. We worked in the same lab for five years, sharing the same office space, HPK-G13. The first photo is from 06/2025, and the second is from 04/2005.
A Day Dedicated to Science: On June 12, the @biozentrum community gathered for its traditional symposium. Bringing together around 300 Biozentrics, the event showcased a broad spectrum of cutting-edge research while fostering interdisciplinary dialogue and collaboration.
Congratulations to @annaleder_ receiving the Shepherd price for her PhD work at today’s @biozentrum symposium @biozentrum_phds . Stay tuned for the official paper release in the coming weeks.
Tired of costly cloning software? Try IVA Prime: a free, game-changing tool for automated primer design in IVA cloning! Simplify complex cloning with one click, reduce errors, and save time. Visit ivaprime.com. doi.org/10.1093/nar/gk… collaboration with @JGarciaNafria
Check out our latest story on the cryoEM structure of the BAM holo insertase complex! Out in @ScienceAdvances (science.org/doi/full/10.11…)
Big week ahead for our lab! @annaleder_ presents at the 1.2 GHz inauguration in Zurich, and @GuillaumeMas2 speaks at @ENC_Conf (5:05pm PT) in Asilomar #ENCISMAR2025. Expect groundbreaking ideas on enzymology, molecular chaperones, LLPS, & ER biology. Don’t miss it!
You are looking for a PostDoc position or know someone who is? We are looking for someone to join our team at @ETH_en Zürich for a project on phage-host interactions of Pseudomonas aeruginosa 🦠🧬👇🏼
Preprint alert 🚨! I present you the second and final manuscript on the BASEL phages! 36 new deeply characterized phages from viral groups that were so far mostly terra incognita - and all infect the E. coli K12 lab strain with easy tricks. 1/12 tinyurl.com/3xdt65f5
Welcome to the 28 students and post-doctoral researchers from all over the world who are starting today the @EMBO Practical Course on structure, dynamics and function of biological macromolecules by #NMR , organized @IBS_Grenoble by @MaleneRJensen : meetings.embo.org/event/24-nmr
We are delighted to announce we @NCCR_AntiResist are funding a four-year PhD position with the Boeck lab in Infection Biology, focusing on pulmonary Pseudomonas aeruginosa infections using genomic and large-scale wet lab technologies. 👉Read more: nccr-antiresist.ch/join-us/
Amazing organisation for the @ICMRBS #NMRchat #ICMRBS in Seoul. We learned a lot from the Korean organization team and are looking forward to see you at the ICMRBS 2026 in Davos Switzerland. Mark it in your calendar!
Great time @ICMRBS #NMRchat #ICMRBS in Seoul. Come an visit our booth for the ICMRBS 2026 in Switzerland - free Swiss chocolate provided 🐮
Honored to receive the J.C.W. Shepherd Prize for scientific excellence. Thanks to the BZ committee @biozentrum for selecting our work.
Nature review paper: Sophisticated natural products as antibiotics go.nature.com/3A3BgSe
It was nice applying #NMR_Spectroscopy on your de-novo designed β-barrels. We love β-barrels! :)
Our nanopore design paper is now published! We developed computational methods to design de novo pores with custom size, conductance and shape. We hope the technology will advance a range of sensing applications. @structbiolbxl @VIBLifeSciences @_VIB_AI science.org/doi/10.1126/sc…