HemOnc Today

Up to 12% of #colorectalcancer cases occur among people younger than 50 😲   📈 What is driving the ‘alarming’ spike in incidence?   💡 @GoHealio shares insights from experts @MSKCancerCenter @VUMChealth @UCSFCancer @OntadaOncology. bit.ly/4lMTCtG

❗ BRCA mutations increased risk for breast-implant anaplastic large cell #lymphoma 16-fold ❗ The lymphoma is a slow-developing rare malignancy associated with textured breast implants after mastectomy for #breastcancer. bit.ly/45jUCQ2

🔎 Diagnostic AI algorithms had ⬇️ sensitivity & specificity for #melanoma when tested on a multimodal, public dataset, according to data in @NEJM_AI. “The public evaluating data algorithms independently is very important.” healio.com/news/dermatolo… @StanfordHealth @HemOncToday

🦠 Childhood exposure to an #EColi produced toxin may increase risk for early-onset colorectal cancer, data in @Nature showed.   In this Healio Exclusive, #GIOncology experts discuss the potential role of #colibactin in this global health challenge 👇 bit.ly/4lMTCtG

😖 Breast cancer survivors often talk about #chemobrain — or reduced cognitive function — after treatment. Su-Min Jeong, MD, of @SeoulNatlUni said they should feel reassured after data showed survivors had lower risk for Alzheimer’s disease. bit.ly/4kZoiXB

❌ An FDA advisory panel voted down two different #Blenrep combos for #MultipleMyeloma. 📝 @HadidiSamer of @uamshealth advised researchers to “examine multiple doses … to optimize the best” before conducting large clinical trials. Read more 👇 bit.ly/4f3LPoX

🗨️ “It’s the best single agent treatment that we ever developed for metastatic #breastcancer.” @PTarantinoMD of @DanaFarber @Harvard on the real-world efficacy of trastuzumab deruxtecan, published in @ESMO_Open. @AstraZeneca @DaiichiSankyoUS bit.ly/4f2XQL3

🤖 Study in @NEJM_AI shows AI algorithms need better training to diagnose #melanoma. Robert Novoa, MD, @StanfordHealth told @GoHealio prospective, publicly available datasets are needed to learn how well algorithms perform in the real world. healio.com/news/dermatolo… @HemOncToday

🚨 A predictive tool for hemodynamic instability may soon be coming to the aid of #cancer patients. @AirStripHealth’s AHI system flags early signs of #sepsis or decline in #immunocompromised cancer patients, giving providers time to act 🏁 bit.ly/44ITFAI

🗨️ “Every bit of movement counts.” Walking or household chores can be enough #physicalactivity to lower risk for certain cancers, according to data in @BJSM_BMJ. Healio spoke with a predoctoral fellow at @theNCI about light-intensity physical activity. bit.ly/4lRjXq4

An #FDA advisory committee ruled against two different #Blenrep combos for #MultipleMyeloma. 📝 Despite the decisions, @RahulBanerjeeMD of @fredhutch @UW remains “cautiously optimistic” due to PFS benefit in phase 3 trials. Read more👇 bit.ly/4f3LPoX

🗨️ “The sheer magnitude of the escalation was truly staggering.” Healio spoke with @Coolspace3 of @GeisingerHealth about data in @cureusjournals that showed a nearly 219% increase in opioid-related deaths with GI complications from 2010 to 2020. #Opioid bit.ly/4nSWFSC

🆕 In this Residency to Retirement column, @OJMGroup experts explain why taxes matter when choosing where to retire. Physicians should consider: 🟢 State and local taxes 🟢 Property taxes 🟢 Sales and excise taxes 🟢 Cost of living, and more 🔗 healio.com/news/hematolog…

🚫 FDA slams brakes on Replimune’s RP1 ➕ nivolumab for advanced #melanoma. Company left “surprised” and “disappointed” by rejection – so what comes next? bit.ly/4f0Tu7r

🧬 What if you could match cancer patients to the right treatment… in 10 days? @firstascentbio’s functional #PrecisionMedicine platform pairs tumor testing ➕ FDA-approved drugs to craft care “as personal as a fingerprint,” said CEO Jim Foote. #CancerX bit.ly/46TU0BS

🛑 #FDA delivers setback for #Columvi in relapsed or refractory diffuse large B-cell #lymphoma as STARGLO fails to measure up for 2⃣nd line therapy in U.S. patients Genentech “disappointed” but “remains confident” the drug could still pivot... healio.com/news/hematolog…

Keep your CME simple, fast, and tailored to you. With the Healio CME app, you’re always just a few taps away from your next credit. Download now: bit.ly/4kMmSPY #HealioCME #FreeCME #MedicalEducation

❗ More than 80% of #breastcancer survivors report changes and distress about their #sexualhealth. Most also say they are not getting the help from their health care team they desire. 🚨 Alarming numbers from @JCOOP_ASCO. bit.ly/46op1ho

🦠Fungi have led to significant medical advancements, such as penicillin and statins. Now, researchers @Penn are trying to transform molecules from aspergillus flavus into a #leukemia treatment. @XueSherryGao @PennEngineers @pennbioeng @nchembio bit.ly/46INspH

It's been a busy week in #lungcancer 🫁 🏃‍♀️Even light physical activity reduces #cancer risk 🩸Lowering BP has no impact on new cancer risk 🧬Only 40% of advanced cancer patients receive next-gen sequencing 🎧We recap the headlines you need to know👇 healio.com/news/hematolog…