Giampaolo Trivellin

🚨🚨🚨 my lab latest peer-reviewed paper is out @FrontEndocrinol 😃 Check it out for free @ tinyurl.com/28x299ru It reports the identification of PAM (peptidylglycine α-amidating monooxygenase) as a candidate gene associated with pituitary hormone hypersecretion. A 🧵 1/9

Methodologies in pituitary research by Giampaolo Trivellin @GP_R101 Understanding the techniques that have underpinned important discoveries in pituitary research is vital for those hoping to make future breakthroughs 👉 issuu.com/victoria.withy… @EYEScientists

🚀 Excited to Launch “EYRC Interview - Career in Progress,” where we spotlight mid-career researchers shaping the field of neuroendocrinology 🌟 First up: Dr. Nicole Bechmann, a leader in adrenal gland tumor research! Link to the full interview: youtube.com/watch?v=QsCaM5…

🎥 On behalf of the EYRC, Dr. Pedro Marques interviewed Prof. Martin Reincke in Porto, discussing key updates on Cushing’s syndrome, career advice in neuroendocrinology, and the importance of balance in life and science. 🔗 More on LinkedIn: @enea-young-researcher-committee

Neuroendocrinology Watch by EYRC! We are happy to highlight a publication in the EJE by Pérez-Rivas et al.: 🔗 doi.org/10.1093/ejendo… Meta-analysis explores the significance of USP8 variants in corticotroph tumours. 🔗 More on LinkedIn: @enea-young-researcher-committee

⚡️ Only 1 week to go! The final countdown has begun — make your research count! 🧠 Submit your abstract for the 12th EYES Meeting 2025 before July 6! 📍 Milan, Italy | 🗓 26–28 September 2025 @ESEndocrinology @waltervena4 @juanma_jv22 @KSaravinovska @AltieriBarbara

🚨 New Neuroendo Watch by EYRC – Highlight Alert! We spotlight a study that investigates how acromegaly alters the innate immune system independently of glucose metabolism. 📷Full post with takeaways on our LinkedIn page: linkedin.com/company/enea-y…

📣 Thrilled to announce our next speaker for the EYES Annual Meeting in Milan – Prof. Constantine Stratakis! 💡 Register & submit your abstract! ⏳ 🇮🇹 Join us in Milan! @waltervena4 @juanma_jv22 @KSaravinovska @AltieriBarbara @ZibarKarin @ESEndocrinology

🕒 Can restoring cortisol rhythms improve outcomes in Cushing's Syndrome? A new study suggests once-daily osilodrostat may enhance sleep & QoL via chronotherapy! 🌙 👉 Full breakdown on our LinkedIn page: linkedin.com/company/enea-y…

High prevalence of deleterious germline variants in cancer risk genes among subjects with young-onset, sporadic pituitary macroadenomas medrxiv.org/cgi/content/sh… #medRxiv

🎥 Just out! Dr. Pedro Marques interviewed Prof. Anton Luger at the 2025 Portuguese Endocrinology Congress 🇵🇹✨ Watch the full interview on LinkedIn: linkedin.com/company/enea-y… and YouTube via EYRC: youtu.be/C8xxIGnydrk

🚨 New Neuroendo Watch by EYRC – Highlight Alert! We spotlight a study revealing how cholesterol metabolism drives dopamine agonist resistance in prolactinomas. 🧪 Full post with takeaways on our LinkedIn page: linkedin.com/company/enea-y…

🧠 New EYRC Neuroendocrinology Watch! Cabozantinib significantly prolongs PFS in patients with pancreatic & extrapancreatic NETs. 📊 Phase 3, placebo-controlled, multicenter study 🔗 More insights on LinkedIn: linkedin.com/company/enea-y…

💡April 8 is Cushing’s Disease Awareness Day 💡 A rare but serious condition often missed or misdiagnosed. Early diagnosis can change lives. #CushingsAwareness #RareDiseases

Delighted to see this published in @EJEndo after many years of work Forever grateful to Prof Márta @KorbonitsL for giving me the chance to work on this Reassessing the role of the p.(Arg304Gln) missense AIP variant in pituitary tumorigenesis academic.oup.com/ejendo/article…

🚀 Neuroendo Watch We highlight a study in Endocrine with new insights into MEN5 📌 First reported case of pituitary gigantism linked to a germline MAX mutation 📌 Identification of myelolipoma as a new disease association  📌 Expansion of the MEN5 phenotype beyond  (PPGLs)

Neuroendo Watch: AI-assisted surgical decision-making tool by Bou-Nassif et al. ✅ AI-powered tool analyzes millimetric tissue fragments intraoperatively ✅ Differentiates normal pituitary vs. adenoma with high accuracy ✅ Useful in centers without a neuropathologist

📢 Neuroendo Watch highlighting Matsuda et al. on adam/papi Craniopharyngiomas (A-CP/P-CP) 1️⃣ M1 macrophages > mostly in ACP & M2 macrophages > in PCP. 2️⃣ M1:M2 ratio was asso. with AVP deficiency & panhypopit. 3️⃣ Cell-cell interactions, particularly involve CD44-SPP.

🔆NeuroEndocrinology Watch🔆 “Personalized Algorithms Based on Urinary Free Cortisol in ACTH-dep. Cushing’s” Lavoillotte et al., JCEM •UFC <3x ULN excludes ectopic CS (ECS) •UFC 3-10x ULN →low ECS prevalence •UFC >10x ULN →CT recommended •24h-UFC accurately predicts ECS

🔆 Neuroendocrinology Watch 🔆 “Phenotype of Pediatric Cushing Syndrome without Obesity” Padilla C et al., EJE, 2024 • Non-obese patients: older, mostly female, advanced puberty. • Different BP profiles by obesity status. • Weight gain not the only clue—screen for hypercort.

🔆 Neuroendocrinology Watch 🔆 highlithing Lin B et al., Adv Sci 2024, reveal microbiome-metabolome links in craniopharyngioma. - ↑ Clostridium & disrupted purine metabolism - Hypoxanthine ↔ hypothalamic comorbidities - Redox imbalance fuels CP progression