GB
@GMBurslem
Chemist/Chemical Biologist. Assistant Professor at Penn (@BB_UPenn). Confused Brit in the US. Views my own. He/him
Fascist leaders don't seize power, they get invited in by people who have decided that actually, they just couldn't care less, turning a blind eye to all the evident problems, ignoring the dangers faced by the weakest in society, and simply hoping they will personally benefit.
Excited to share our new @ScienceMagazine paper! Led by postdocs Ruchao Peng and Xin Xu, we used cryo-EM/ET to reveal the influenza ribonucleoprotein complex structure and its strand-sliding mechanism for RNA synthesis, paving the way for new antivirals. science.org/doi/10.1126/sc…
New preprint with Eddie Lees lab!
Maybe my last Tweet? We found that shifting around polyubiquitin (using a chemical biology trick) results in altered #tau filament structure. The unstructured "fuzzy coat" of tau filaments matters!?! #AD #FTD #FTLD #cryoEM #Alzheimer #VCP #raredisease biorxiv.org/content/10.110…
Check out our work on protein editing!
A pair of split inteins—small protein segments that can undergo a self-sustained protein splicing reaction—enables endogenous protein editing in living mammalian cells, according to a new study in Science. 📄: scim.ag/3ENypj9 #SciencePerspective: scim.ag/430jwC9
Pairs of split protein segments can modify a variety of target proteins in a living cell @ScienceMagazine @ophirshalem @JennaNBeyer @GMBurslem science.org/doi/10.1126/sc… science.org/doi/10.1126/sc…
Happy Women’s History Month from @RTAatPennMed @PennMedicine! Check out our events planned for the rest of the month!
Check out our March newsletter!
We have a postdoc position available for a very cool collaborative project! Synthetic chemistry expertise is a must! Unfortunately due to the funding source, this position is only available to US citizens or permanent residents. chemistryjobs.acs.org/job/postdoctor…
First paper of the year is online! Happy to have made a small contribution to this paper from the @ShorterLab #lysinePTMs
Opposing roles of p38α-mediated phosphorylation and PRMT1-mediated arginine methylation in driving TDP-43 proteinopathy: Cell Reports cell.com/cell-reports/f…
Interested in applying a chemical biology approach to ubiquitin signalling? Elton Zeqiraj and I are currently recruiting a postdoctoral researcher in this area! jobs.leeds.ac.uk/vacancy.aspx?r…
🚨‼️ The December 9th abstract deadline for @ASBMB #ASBMB25 in Chicago is coming up fast! Need tips on crafting an accessible abstract? We’ve got you covered—check them out here! 🚨‼️
🧠Show the world what's possible! Submit your abstract for #ASBMB25 by Dec. 9: bit.ly/3YGLQIx. ➡️Here's an abstract-writing tip from Daniel M. Raben: "Avoid jargon that only those in the field would know." bit.ly/3ADfSnv #Neurobiology #ASBMB25
ABRCMS 2024 is here in Pennsylvania! We're excited to be here to represent @PennMedicine & share information on @IDEAL_Research #PennPREP #SUIP, our 7 @pennbgs graduate groups, & PennMSTP @houseofbrass! Come see us at booth 1235!
Apropos of nothing, please protect every queer and trans person you know in absolutely every way you can
Interested in high-throughput chemistry, chemical biology and kinases? @MWrightLab @baylisslab and I are recruiting a PhD student as part of a collaborative team to work in this area! phd.leeds.ac.uk/project/2067-h…
Please go and vote! I would dearly love to be able to vote in the country I’ve make my life in, please don’t give up that opportunity/power if you can!
Interested in pursuing your PhD in biochemistry, biophysics or chemical biology?! Come and join us at @BB_UPenn! Our @BMBGGUPENN applications are open! Info here: med.upenn.edu/bgs/phd-applic…
Congratulations to Dr @JennaNBeyer!! The newest PhD from @BMBGGUPENN and the first PhD from the lab!
Exciting news! @BB_UPenn has installed a new 800 MHz NMR instrument, supported by @HHMINEWS & @PennMedicine. Special thanks to @tolbertrnalab for making this possible. This cutting-edge resource will be invaluable for our @BMBGGUPENN grad students & the entire Penn community.
Pooled endogenous protein tagging & recruitment for systematic profiling of protein function ft. @YSereb, Deepak Mani, @ophirshalem (@PennGenetics/ @CHOP_Research), @MaujeanT & @GMBurslem (@BB_UPenn/ @Penn_CBIO/ @PennEpiInst) @CellGenomics tinyurl.com/3ujy38er
PSOM PhD students Brianna Hill-Payne and Sam Preza were recognized at a national level for their passion for #research and #diversity in biochemistry and bioengineering, as recipients of the prestigious Howard Hughes Medical Institute Gilliam Fellowship. spr.ly/6016oz6kK