Frank Yeh
@FangChengYeh
Research parasite • DSI Studio & U-Net Studio • Taiwanese Dad of 4 • Proverb 3:5-7
The #FiberDataHub is approaching 50,000 ready-to-use datasets and now has a citable reference: nature.com/articles/s4159… Though often used with #DSIStudio, the hub is an independent resource that can be accessed using Python and used by DIPY, MRtrix and other tools!

A new study from the lab @NatureMedicine Over 6,000 proteins, more than 10,500 individuals. #Alzheimers, #Parkinsons, and #FTD. @Ali_bioinformtx maps the shared and disease-specific plasma proteomic landscape of neurodegeneration @WashUNeurology nature.com/articles/s4159…
1/11 Excited to share our @Naturestudy led by @Leon_Oo1 @csabaorban @ZShaoshi doi.org/10.1038/s41586… It is well-known that AI performance scales with logarithm of sample size (Kaplan, McCandlish 2020), but in many domains, sample size can be # participants or # measurements...
The thalamocortical structural connectivity shown in this Nat Neuro paper by Valerie Sydnor and @sattertt 🔗 nature.com/articles/s4159… Looks remarkably similar to a tract-to-region connectome of the thalamocortical pathway. Fascinating work!

This Nat Neuro study shows the importance of quality control for T1w cortical thickness estimation. (QC is also important for DWI data!) nature.com/articles/s4159…
This paper reports subtypes of AD related to specific pathways. Perhaps differential tractography could help identifying them? academic.oup.com/brain/article/…
🏆 Achievement unlocked: Temporarily banned from NDA for downloading too much data (42TB in 30 days, limit was 20TB) to create ready-to-use fiber data for #FiberDataHub (brain.labsolver.org now nearing 50,000 scans!). I'm banned so you don't have to be! 😂


One of the largest #schizophrenia #DTI datasets (~400 patients) is now available on #FiberDataHub (brain.labsolver.org) (data-nih/nda/nda-2098/) To my knowledge, no tractometry or tract-to-region analyses have yet been conducted on this dataset—lots of opportunities ahead!


🧠 Exciting opportunity alert! The Beyond FA Grand Challenge at #MIDL2025! This challenge is pushing the ML & neuroscience community to go beyond traditional fractional anisotropy maps and extract meaningful features to better understand white matter integrity in Alzheimer's…
Fiber Data Hub now includes two large brain tumor datasets (data-nih/tcia at brain.labsolver.org): 🧠 UPenn-GBM (~600) 🧠 UCSF-PDGM (~400) I've fixed the original DWI—without these fixes, they wouldn't be usable for tracking! Now we can track any of the ~1,000 patients.


New HCP disease studies are now available at Fiber Data Hub. brain.labsolver.org🧠 Already have an NDA access agreement? Contact me for access to preprocessed data!

