Pharmaceutical Science at FIP
@FIP_BPS
FIP’s Board of Pharmaceutical Sciences sharing the latest news and views with scientists around the world.
This year, we celebrate 100 years of pharmaceutical sciences at FIP! Learn more about the formation of the Board of Pharmaceutical Sciences in 1925 in the Pharmaceutical Science Newsletter: fip.org/publications?p….
In this perspective from Maria Laura Bolognesi and team, the UN Sustainable development goals are placed in the context of medicinal chemistry and outlines how we can “turn words into actions”. pubs.acs.org/doi/10.1021/ac…
"Pharmacy practice research is the key to advancing global health," says Victoria Cardenas, Chair of the @FIP_PPRSIG. Read the full interview in the BPS newsletter – available in the FIP Library: fip.org/publications?p….
Giovanni Pauletti, @FIP_BPS chair, shares his vision for strengthening pharmaceutical sciences & empowering the next generation of scientists to drive innovation.📖Read the full interview in this month’s International Pharmacy Journal (IPJ): fip.org/publications?i….
A blood-first assay screening trial found entrectinib equally effective in advanced/metastatic non-small cell lung cancer patients diagnosed by liquid biopsy or tissue testing, achieving an 81.5% response rate. More in @NatureMedicine: nature.com/articles/s4159…
FIP’s Pediatric Formulations Focus Group study on paediatric compounding was featured in @HPE_magazine last week: bit.ly/3WsQSHf. Lead author & focus group chair Hala Fadda discusses off-label prescribing in paediatrics, & the study’s findings & recommendations.
Personalised brain circuit scores reveal six biotypes in depression and anxiety according to a study by @StanfordMed, USA. These biotypes predict symptoms, behaviour & treatment response, paving the way for precision psychiatry. More in @NatureMedicine: nature.com/articles/s4159…
A personalised dietary programme can significantly improve aspects of cardiometabolic health compared to standard dietary advice, according to a randomised clinical trial conducted by the @KingsCollegeLon, UK. More in @NatureMedicine: nature.com/articles/s4159…
Optimising magnesium stearate content & low-shear mixing improves aerosolisation in carrier-based dry powder inhalers, establishing a correlation between rheological parameters & fine particle fraction. More in the International Journal of Pharmaceutics: sciencedirect.com/science/articl…
An organic-solvent-free method for peptide encapsulation in poly(lactic-co-glycolic acid) microspheres has been found by researchers from @UMich, USA, to offer sustained in vitro peptide release for over 56 days. Read more in @NatureComms: doi.org/10.1016/j.jcon…
NMR and X-ray scattering methods were used by researchers from @Chiba_Univ_PR, Japan to examine how mixing sequence impacts structure & efficacy of small interfering RNA (siRNA)-loaded lipid nanoparticles . More in @JControlRel: doi.org/10.1016/j.jcon…
Monoclonal antibodies against Acinetobacter baumannii, a multi-resistant bacteria associated with hospital-acquired infections, have been developed using genetically engineered mice by researchers at @Cambridge_Uni, UK. More in @NatureComms: nature.com/articles/s4146….
MED6-189, a compound inspired by marine sponge extracts, has demonstrated effectiveness against drug-sensitive & drug-resistant Plasmodium falciparum strains in vitro & in humanised mouse models, report @UCRiverside & @YaleMed, USA, in @ScienceMagazine science.org/doi/10.1126/sc…
The role of pharmacists in deprescribing proton pump inhibitors is the research focus of Syed Arman Rabbani, associate professor @rakmhsuofficial, UAE🇦🇪, reflecting a commitment to optimising drug therapy and enhancing patient care.
A kidney organoid-based proximal tubule-on-chip (OPTECs-on-Chip) that closely mimics in vivo renal physiology has been developed by a team @KyotoU_News, Japan. More in @iScience_CP: bit.ly/3NmkGAw
New strains of Acinetobacter baumannii, a top priority pathogen identified by @WHO due to its role in multi-drug-resistant infections, have been engineered by @LivUni, UK, facilitating the development of medicines targeting this bacteria. More here: journals.asm.org/doi/10.1128/aa….
A new method to target GTPase enzymes linked to cancer & neurodegenerative diseases has been discovered @UCSF, USA. Researchers tested K-Ras-targeting drugs on other mutated GTPases, revealing new drug-binding sites. Findings in @CellPressNewsl: bit.ly/3YjGl2j.
The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by @ucl, UK. The study shows that different sequence variants in the gene form distinct DNA structures, impacting insulin regulation. More in @NatureComms: nature.com/articles/s4146….
The impact of tumour microenvironment & metabolism on cancer development, drug resistance & metastasis is the focus of María Virginia Giolito’s research at @IREC_UCLouvain, Belgium. This series is produced by @FIP_NGPS (part of the FIP Board of Pharmaceutical Sciences) & @FIPECPG
A new method for synthesising nickel-alkyl complexes, which facilitates selective alkyl–alkyl cross-coupling, has been developed by @OhioState, USA. This advancement allows for rapid diversification of amino acids & pharmaceuticals. More in @nature: nature.com/articles/s4146….
