Robert Hänsel-Hertsch
@EpiStrucStab
Junior Group Leader, Center for Molecular Medicine Cologne, University of Cologne, DE
Here’s a brief summary of what we found: Using #cryoEM, we found the chromatin regulator complex PRC2 to form dimers on chromatin. PRC2 dimerization had been shown before, e.g. by Tom Cech, @KJArmache, Xin Liu (UT Southwestern), @vignesh_k757 labs
Fantastic story, achievement and congratulations to all of you! Happy that we could contribute.
We can finally present our work on PRC2 dimerization on chromatin published in @MolecularCell! What a journey this has been, it could only be accomplished because of the ceaseless effort by Egor and @paulvictorsauer doi.org/10.1016/j.molc…
Wonderful collaboration with @NogalesLab first an foremost, but also invaluable work by @KarissaScience, @EpiStrucStab, Farnusch Kaschani and their groups, with support by @crc1430 and @CanTarNRW
Please to share our work published in @iScience_CP comparing #cfDNA and small #extracellularvesicle DNA sequencing from the plasma of lung cancer patients. #liquidbiopsy cell.com/iscience/fullt… [cell.com]
‼️Happy to share our study on #LUBAC mediating the tumorigenic potential of #LTBRsignalling. Amazing team work and super happy to be part of it!! @UKKoeln @uclcancer #IBMG @Uni_Stuttgart @sfb_1403 @sfb1399 #sfb1530 @cddpress nature.com/articles/s4141…
🔬 Exciting News! @ina_huppertz ,@spanier55 and @AndreasBeyer012 are members of the new SFB 1678, exploring the impact of fidelity changes in mRNA & protein biosynthesis on aging and disease. @CECAD_ @UniCologne #ScienceResearch #Aging #Ageing age.mpg.de/403407/new-col…
🧬 In this new perspective article, Joana Frobel and Robert Hänsel-Hertsch discuss the link between G-quadruplexes and #genomeinstability in #ageing 👴 Read it here: ➡️ doi.org/10.1002/1873-3… @EpiStrucStab
I am beyond thrilled to take part in the new #CRC1678 consortium! Very much looking forward to the exciting work ahead on mRNA and protein fidelity. All made possible by the exceptional leadership of @AndreasBeyer012. Stay tuned - we will be hiring soon!
#CRC1678 Fantastic news: our new CRC on systems-level consequences of fidelity changes in mRNA and protein biosynthesis gets funded by @dfg_public! This is an amazing team effort - 1000 thanks to everyone involved, the great reviewers and the DFG team! 🎉
Feeling privileged to work with these outstanding groups. 🍾
#CRC1678 Fantastic news: our new CRC on systems-level consequences of fidelity changes in mRNA and protein biosynthesis gets funded by @dfg_public! This is an amazing team effort - 1000 thanks to everyone involved, the great reviewers and the DFG team! 🎉
New hypothesis from our lab! Explore the age-related decline of helicase function and its impact on genome instability. Discover how G-quadruplex structures might drive DNA damage in aging. 🧬 #Aging #Sirtuins #Helicases #Gquadruplex #Rloops 🔗 Read more: febs.onlinelibrary.wiley.com/doi/epdf/10.10…
🚨Job Alert! Interested in the 🧬#epigenome and #cell_fate_decisions? We are looking for a highly motivated #postdoc to join our multi-disciplinary lab at @CMRI_AUS 🇦🇺. See below for more details. Please RT seek.com.au/job/72141110
Join us in investigating epigenetic mechanisms in small cell lung cancer (SCLC)! Are you passionate about unravelling the mysteries of cancer epigenetics and driven to make a difference in combating SCLC? Look no further! @sfb1399 👉jobs-uk-koeln.de/index.php?ac=j…
Accelerate or stop? Just out in @NatureGenet: why is it possible that during aging on the one hand RNAPII elongation speed increases, while on the other hand RNAPII stalling increases as well? Find the answer here: nature.com/articles/s4158…
Ernesto: We got the cover @neto_flames @sketchscience!!! Super happy to share the issue with great colleagues such as my benchmate during my postdoc times @William_Mair and current/former Cologne neighbours @petertessarz @ChrysaNikop
🗞️Our November issue is out! Read about #spermidine in reproductive aging, methylation and heterochromatin in #HSC aging, #neovascularization, and much more. 🎨 Image courtesy of Ernesto Llamas, cover design by Lauren Heslop. nature.com/nataging/volum…
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