James Hoffman
@Drjhoffmanmiami
Associate Professor, Myeloma/Amyloidosis Program; Associate Director heme-onc fellowship program at @sylvestercancer at U. Miami; Miami sports fan; father of 3.
From my 7th grade class journal- 1987- still haven’t hung out w @DanMarino but enjoy getting to practice medicine in my favorite city every day. Still get excited before @MiamiDolphins season begins- should be a fun year!

Lighting the final night’s lights… hoping for a year of peace and health for all!

Why UM/Jackson is an incredible place to train for Hematology-Oncology fellowship: 🌟 NCI-Designated Cancer Center @SylvesterCancer with access to cutting-edge clinical trials and a highly diverse patient population 🩺 Fellows-run continuity clinic at Jackson Memorial where you…
🚨 Tocilizumab Prophylaxis for Patients with Multiple Myeloma Treated with Bispecific Antibodies Critical to Move all Future BiTEs to outpatient especially in community clinics 🧵1/Can we prevent CRS in myeloma patients receiving bispecific antibodies? New real-world data from…
Our CD38 resistance story is out in @BloodPortfolio. We had a great time putting this one together. Big multi-institutional collab!
Happy to share our new work out today on @BloodPortfolio #Blood where we report CD38 loss as recurrent mechanisms of resistance to anti-CD38 antibody in multiple myeloma. Great collaboration between @MSKCancerCenter @MSK_DeptOfMed @UCalgary @HDMyeloma @MayoClinic #mmsm #wgs
Breaking News: @ProthenaCorp has announced that the Phase 3 AFFIRM-AL clinical trial evaluating birtamimab in patients with Mayo Stage IV AL #amyloidosis failed to meet its primary endpoint. Learn more: arci.org/negative-affir…
Anyone who has taken care of cancer patients knows that there are many unique trajectories. The only reasonable take is- this is sad… but everyone wants conspiracies and clicks…
Prostate cancer is the easiest cancer to diagnose when it first starts and to watch it progress to bone metastases. The PSA blood test shows the rate of cancer cell growth. For even with the most aggressive form, it is a 5-7 year journey without treatment before it becomes…
Interesting decision for the FDA re: data in SMM… I also have my reservations (and don’t use dara myself for SMM)
As I mentioned y'day... FDA questioning the benefit-risk of $JNJ $GMAB Darzalex in smoldering myeloma. This is from the FDA's review, posted this morning.
Cilta-cel associated Parkinsonism remains a challenge. Instead of going right to high dose Cy which can be toxic to circulating CAR T cells, we opted to try intrathecal chemotherapy in 5 consecutive cases. 4/5 pts had a response and 3 complete resolution! IT chemo seemed to be…
Announcing 2025–26 Chief Fellows @Jani_Chinmay & Dr. Amrit Paudel Dr. Jani, former chief resident @MAHIMRes @harvardmed is working on translational/Phase 1 research in lung & GU cancers. Dr. Paudel, former faculty at @Georgetown, focuses on sarcoma research esp Myxofibrosarcoma.
Really cool AI based skin cancer detection effort spearheaded by a UM medical student Yasmine Mohseni- any doctors can help by filling out this form - docs.google.com/forms/d/e/1FAI…
Excited to see our fellows actively participating at the @FLASCO_ORG #Fellows Conference, with two fellows @Jani_Chinmay @DeborahSoong presenting at the Navigation Panel! A fantastic opportunity to connect, collaborate, and contribute.
The Dolphins are raising a lot of money for cancer research in their annual Cancer Challenge bike race this weekend. To contribute, here's the link. Always a great event dolphinscancerchallenge.com
I really don’t get it. People that disrupt classes like this should be ejected from campus and trespassed if they return. It’s not complicated. Free speech isn’t the right to speak anywhere you want.
BREAKING: Fully masked terror-supporting students broke into a Columbia University class of Jewish students and began handing fliers of Jewish stars burning with "Curse Zionism" written. Columbia should lose its accreditation and federal funding immediately. Enough of this!
There are 100+million more people in US vs 1980 Obesity rates have tripled vs 1980 median age in the US is 10 years older vs 1980-baby boomer avg age now 70 Yes- we pick up more cancers-need to avoid overtreating But sure- issue is too much trust in oncologists ridiculous.
Don’t trust your oncologist.
Hem/onc fellowship secret Santa! 🎄🎅🏼@HemOncMiami @SylvesterCancer
A late entry into the stupidest tweet of the year… and I think it’s a winner
I fully believe vaccines cause Autism. It’s another example of crimes against humanity. And innocent babies, children, and their families are the victims.
This is a sickening and morally bankrupt take. Insurance execs are “architects of mass death” so it’s open season on them? When did cold blooded murder on our cities streets become a “nuanced” issue. Heads of hospital systems next? Pharma company execs?
It *is* a healthcare debate, actually. And only multimillionaires who never have to worry about their loved ones dying preventable deaths because of the cruelty of Brian Thompson would demand public sympathy for an insurance CEO: an architect of mass death. Watch in full.
We are thrilled to announce the successful fellowship match for our program @UMiamiHealth @SylvesterCancer @JacksonHealth . Please join us in welcoming our new fellows for upcoming academic year.@Valardilaavila @AsadARauf @dan_morgen , Derek Essegian and Jose Forero.
Excited to share new pre-print from the lab! @BenDiamondMD investigated 580 WGS to define the mutagenic impact of radiotherapy in hematological malignancies. Great collaboration between @HDMyeloma @MoffittNews @SylvesterCancer @MSKCancerCenter 1/19
As a 50th birthday present to me, a close friend has thrown out a challenge to match a total of $500 to Dolphins Cancer Challenge for any donations made today! If we raise $500, $500 will be donated. Please share/help if you are able! #OneTeamOneFight dolphinscancerchallenge.com/index.cfm?fuse…