Steven Devine
@DrStevenDevine
Chief Medical Officer @NMDP_Org, Senior Scientific Director @CIBMTR Tweets are my own.
Proud to share @JCO_ASCO paper of the ACCESS study run by @CIBMTR and sponsored by @nmdp_org 145 recipients of MMUD grafts using PTCy experienced outcomes similar to matched transplants, including <7/8 grafts. 59% of patients were diverse!
An incredible amount of work with really brilliant people made #BMTCTN1703 a success and the new SOC for #GvHD prophylaxis #PTCyRules #BMTCTN @CIBMTR Post-Transplantation Cyclophosphamide-Based Graft-versus-Host Disease Prophylaxis | NEJM nejm.org/doi/full/10.10…
Clinical Impact of Cryopreservation of Allogeneic Hematopoietic Cell Grafts During the Onset of the COVID-19 Pandemic ashpublications.org/bloodadvances/… Our @CIBMTR analysis of outcomes of cryopreserved grafts during the pandemic. OS same; but risk of relapse and PGF higher with Cryo.
Amazing work by @KeanMD and her team, @CIBMTR @BeTheMatch and many others for achieving first ever @US_FDA approval for a drug to prevent acute #GVHD. Historic day for BMT field!
#ASH21 Oral: The 𝐔𝐧𝐬𝐭𝐨𝐩𝐩𝐚𝐛𝐥𝐞 @CIBMTR @BTMPublicPolicy @BeTheMatch 👏:Neither COVID19, Nor Cryopreservation, Prevented Allogeneic Product Infusion. ✔️9294 collected, 9085 infused ✔️544 ave infused/mo ✔️Recipients of COVID+ donor did not acquire infection @DrStevenDevine
Activation alert! #BMTCTN 1903/AMC-109 Auto-RESIST study is open to enrollment: Administration of HIV-specific T cells to HIV+ Patients Receiving High Dose Chemotherapy Followed by Autologous Stem Cell Rescue clinicaltrials.gov/ct2/show/NCT04… @DunleavyKieron @DrStevenDevine @AMC_Studies
Although #BMT is the only known cure for MDS, many people aren’t aware of BMT or think that they’re too old to have one because of its side effects. Learn more about this @BMTCTN study: cibmtr.org/ReferenceCente…
Great to be back live @ASTCT CRTC. Looking forward to working with the wonderful scholars and great faculty.#ClinicalResearch #bmtsm #tcellrx
Finally a return to live events for @ASTCT. The Clinical Research Training Course begins July 14th. Best wishes on the event and thank you CRTC faculty. #clinicalresearch #LiveEvent #postcovid astct.org/events/event-d…
Important @cityofhope study with encouraging results in MMUDs using PBSC and PTCy. Further rationale for soon to be activated @BeTheMatch NMDP MMUD study called ACCESS. ashpublications.org/bloodadvances/…
GREAT talk from @charliecraddock this morning @MDAndersonNews. What he has done for allo-transplant for pts w/ AML, not just for the UK, but for the entire field with a coordinated national network facilitating RCTs to answer the most important questions is very special indeed.
Join our @MDAndersonNews Emil J Freireich Hematology Grand Rounds: “Improving outcomes in patients allografted for Acute Myeloid #Leukemia” presented by @charliecraddock, of @unibirmingham | June 16, 8 am CST | mdanderson.org/research/depar… | #leusm #MedEd #AML
7/ Conclusions: First study of MGTA-145 + plerixafor in multiple myeloma shows promising efficacy for same day mobilization, well tolerated. Looking forward to completing the study and further development of this agent for improving stem cell mobilization. #ASCO21 #mmsm
The Center for International Blood and Marrow Transplant Research (CIBMTR) Launches Study of #COVID19 Vaccine Immunogenicity in Patients With Hematological Malignancies Who Have Received #CellularTherapy businesswire.com/news/home/2021…
We are elated that the TRANSPLANT Act passed! And, our advocates are too!💚💙👏👏 Join our #BTMAdvocateAllStars and share with us what renewing our federal Program means to you!
Increasing Donor Options in Allogenic Hematopoietic Cell Transplantation ascopubs.org/doi/full/10.12… Very nice @JCO_ASCO editorial about @BeTheMatch study that will "rejuvenate" interest in mismatched URD Tx. I agree with @Mohty_EBMT and @Florent_Malard
Post-HCT Cyclophosphamide Boosts Transplant Success medpagetoday.com/hematologyonco…. Nice interview with Dr Bronwen Shaw about @BeTheMatch mismatched URD study recently published in @JCO_ASCO It's about creating good options for all patients regardless of #Race
Did you know that not all marrow transplants requires bone marrow? Peripheral blood stem cells (PBSC) are another option that provide life-saving treatments to patients in need. The PBSC donation process is similar to donating plasma. Want to learn more? ms.spr.ly/6014VWWcn
Finally an 🍎s to 🍎s comparison of donor sources! MUD clearly > Haplo related = MMUD. Important study that shows matching does matter when controlling for GVHD prophylaxis. 15-MMUD results to be published soon as well.
8/8 MUD ptCy > Haplo ptCy. Better matching matters...👇 HLA Haploidentical versus Matched Unrelated Donor Transplants with Post-Transplant Cyclophosphamide based prophylaxis | Blood | American Society of Hematology ashpublications.org/blood/article/…
Last day of a great #TCTM21. We will hear about the results of @BMTCTN 1301 study today presented by @DrMiguelPerales during LBA session. Hard to believe @BMTCTN now nearly 20 years old! Learn more about it's history from our recent review in @JCO_ASCO: ascopubs.org/doi/full/10.12…
I love this video! Could not have been done without our wonderful, dedicated Network partners
Despite facing many challenges during the pandemic, our community continues to thrive. Only together, in partnership with our Network centers, can we continue to thrive and make the impossible, possible. #BeTheMatch #Together
Impact of Conditioning Intensity and Genomics on Relapse After Allogeneic Transplantation for Patients with Myelodysplastic Syndrome @BMTCTN @TheBethesdaLabs @nih_nhlbi @JCOPO_ASCO @LauraWDillon @GegeGui0 @DrStevenDevine @horwi001 @BartScott8 @archerdxinc ascopubs.org/doi/abs/10.120…