Daniel E Spratt
@DrSpratticus
The comments & viewpoints are my own and are not endorsed or necessarily representative of UH CMC, CWRU, NCCN, FDA, NCI, or NRG. They are my personal opinion.
X-torial: Cleaning up the misinformation about @JoeBiden and #ProstateCancer that I am reading everywhere. The purpose of this is to provide education from someone who treats and studies PCa for a living, lead the USA @NCCN PCa guidelines, hold leadership in @NRGonc @theNCI…
Special thanks to @ndesai2005, @DrSpratticus, @AmarUKishan, and Alison Tree for their tremendous input during trial design and @PRIMR_MED for developing/promoting patient-friendly content explaining rationale/hypothesis for the trial.
Let me start by clearly stating: some of my best friends are Urologists. 🙂 But: I worry the response to the SEMS RPLND trial on stage 2a/b seminoma may be over-enthusiastic. If my son gets this dz, I would favor carbo x 1 followed by involved node, low dose proton therapy.🧵
Love the podcast. Thanks for your efforts!
Never a day off for our NRG Podcast team - We're rolling on-site at the #NRG2025 meeting filming on our Veteran Affairs/MTF Subcommittee and VA research priorities for a future episode. NRGOncology.org/Podcast @StephenChunMD @lauren_henke @Baylor
The semi-annual meetings are always a strong call to action for all who serve @NRGonc 💪🏼 For those curious about all things membership and how to get involved, our episode with @dsmgyo was both hilarious and illuminating: 🎧 tinyurl.com/23eywwyw 🍎 tinyurl.com/hxsc8sy4…
Curious about the ins-and-outs of NRG Membership and the NRG Membership Committee? Deputy Group Chair of Membership & Research Integrity @dsmgyo outlines all this information in this episode: nrgoncology.org/Podcast @lauren_henke @StephenChunMD
Wonderful @NRGonc meeting with strong representation from @RadOncUH with @KashaniRojano @lauren_henke @angela_jia_ and more! Leading so many important concepts. Proud of this amazing team.

We are thrilled to continue to be a leading center in radiation oncology with another very exciting collaboration to be the first in the USA to have the most advanced rotational arc cobalt SRS unit available to date (Akesis Galaxy RTI), combined with our amazing LINAC SRS…
UH Seidman Cancer Center is the first medical center in the U.S. to implement the innovative Akesis Galaxy RTi device for patient treatments, while also serving as the flagship site for research and clinical demonstration of this advanced technology. bit.ly/SeidmanX725
In high-risk prostate cancer, radiotherapy plus ADT significantly reduces the risk of distant metastasis compared to surgery-based approaches. However, post-metastasis survival does not differ between treatments. @EurUrolOncol @DrSpratticus @OncoAlert @APCCC_Lugano @Uroweb…
As @NicholasZaorsky said, one more Oscar of oncology in my cabinet 😂😂...Thank you so much @QuadShotNews!! @RadOncUH @DrSpratticus @angela_jia_ Thank you @MRoupret and @EurUrolOncol for your support!!! We need level I evidence for sure....
For those stating this approval was based on a surrogate endpoint this is incorrect. EFS in LA-HNSCC is not a surrogate endpoint for OS. Thus, FDA approved this based on it believing EFS carried independent value. Curious to peoples thoughts if that is a sufficient bar for a…
Pembrolizumab now @FDAOncology approved in resectable LA-HNSCC based off KEYNOTE-689: - mEFS: 51.8 vs 30.4 most (HR: 0.73) - Benefit greater with CPS ≥10 (HR 0.66) - 2yr EFS: 75% vs 62% #OncTwitter #MedTwitter @OncoAlert #ASCO25 #AACR25
Cover Letter and CV Webinar! Upcoming webinar w/ Nicholas Zaorsky, MD, MS, and Chris Corso, MD, PhD, on writing cover letters and CVs for jobs, promotions and beyond! Have a question you want answered? Let us know here: magnetmail1.net/link.cfm?r=ZBB…~~
Combining genomic classifier and digital pathology #ArtificialIntelligence in #ProstateCancer risk stratification. @DrSpratticus @caseccc joins @zklaassen_md @GACancerCenter discuss a study of nearly 10,000 #ProstateCancer patients comparing the 22-gene Decipher® genomic…
Genomic Classifier Decipher® guides treatment intensification in post-prostatectomy patients. Phuoc Tran, MD, PhD @UMmedschool joins @angela_jia_ @RadOncUH to discuss findings from the RTOG 0534 #SPPORT trial examining Decipher® genomic classifier scores as predictors of…
Exciting to bring the tech to USA. I hope the lessons on proton are not repeated. Over 40,000 patients have been treated with carbon ion worldwide. Unclear what cancers this enhances your ability to treat. It is ok to bring new tech and do research with it and not claim it is…
Today, Mayo Clinic opened the Duan Family Building, taking another step in our journey to introduce carbon ion therapy for patients in the Americas. This revolutionary treatment will enhance our ability to treat aggressive cancers. Learn more: mayocl.in/4mYTVme
Genomic classifier #Decipher® guides treatment intensification in post-prostatectomy patients. @tranpt21 @UMmedschool joins @angela_jia_ @RadOncUH to discuss findings from the RTOG 0534 #SPPORT trial examining the Decipher® genomic classifier scores as predictors of treatment…
The Department of Defense Congressionally Directed Medical Research Programs (@CDMRP) recently announced Prostate Cancer Research Program (PCRP) funding opportunities to support innovative, high-impact prostate cancer research. Learn more and apply at cdmrp.health.mil/funding/pcrp.
Curious to peoples thoughts? @seanmmcbride @jamecancerdoc @aleberlin2 @j_luh @DrewMoghanaki @EdwardSchaeffer @montypal @SameerKeoleMD @LPonsky @jryckman3 @xrtGenomics
So when physicians LEAD hospitals, hospitals perform better. Guess what else is true…. When physicians control the board room, hospitals perform better as well. Let’s end the silliness of blocking doctors from owning hospitals. Repeal Section 6001. journals.lww.com/jaaos/fulltext…