Didonna Lab
@DidonnaLab
The Didonna Lab aims at understanding the mechanistic connection between aberrant immune responses and neurodegenerative processes in chronic human diseases.
Congratulations to Prof Espen Spangenburg on wrapping up your first week as chair of the Department of Anatomy and Cell Biology! Your dedication over 10 years has bettered both students and colleagues. Your leadership continues to make an impact.
A new #ScienceReview takes a look at the contribution of neuroinflammation during the course of a range of neurologic disorders, including #MultipleSclerosis, stroke, #AlzheimersDisease, and #ParkinsonsDisease. Read more: scim.ag/3GdAvt4
In @scisignal, researchers identify a molecular hub in neuronal dendrites that shapes the plasticity of synapses and find that the loss of these dendritic scaffolds might play a role in mouse models of Alzheimer's disease. scim.ag/4kawdAV
Thrilled to see the study funded by the Wooten Family Initiative finally published in The FASEB Journal. We show for the first time the involvement of CentA1 in autoimmune demyelination @FASEBorg @ECUBrodySOM @Bunner_Bean @ErzsikePhD faseb.onlinelibrary.wiley.com/doi/full/10.10…
Thrilled to talk about our imaging projects in the lab for the Microscopy Day @EastC
Great discussion group about healthy aging for the STEM@Starlight series @E
Really proud of Cindy Martines, undergrad student presenting the results of her project on ataxin-1 for the Research and Creative Achievement Week! @ECUBrodySOM
“All the science can’t be done in the top five NIH-granting institutions alone. There’s really important reasons to do research everywhere. For the pipeline, the ideas." — Dr. Marisa Bartolomei, @PennMedicine news.ecu.edu/2025/03/10/nat…
Patterns of autoantibody expression in multiple sclerosis identified through development of an autoantigen discovery technology jci.org/articles/view/…
Dr. Marisa Bartolomei from the @PennMedicine gave an incredible lecture on mammalian epigenetics then capped her day at @pittstreetbrewing at a Community and Connection Committee roundtable on mentoring advancing #ECUResearch. #ARRRGH1
Dr. Marisa Bartolomei is the world’s expert on imprinted genes and mammalian epigenetics and a member of the @theNASciences – and she’s speaking to our students tomorrow. When @EastCarolina students pick up a microscope, they have #ECUResearch at their backs. #ARRRGH1
From the high seas to the top tier—#ECU has officially earned #ARRRGH1 status! 🏴☠️ This milestone places us and #ECUResearch among the nation’s top research institutions. See what this means for #PirateNation ➡️ news.ecu.edu/2025/02/13/ecu…
Excited to share our work published this week! Led by myself and world class co-first @gdfnunes working in the @EthanHughesLab in collaboration with Dan Denman: nature.com/articles/s4146…. A short 🧵
Really Happy to have published this article. Thank you to @SfNtweets @NeuronlineSfN for the opportunity. nam02.safelinks.protection.outlook.com/?url=https%3A%…
Mice lacking microglia (Csf1r∆FIRE/∆FIRE) have normal -synapse number and maturation -seizure susceptibility and hippocampal-prefrontal cortex coherence -segregation of inputs into the lateral geniculate nucleus -neuronal and astrocytic gene expression nature.com/articles/s4159…
Another great idea of my students for the annual departmental door contest 🎅
It was an honor to present my research in an outstanding neuroimmunology session moderated by @AkassoglouLab #CellBio
Robin from the Litwa lab explaining with great passion and competence her undergrad project on tuberous sclerosis at #Cell
