DevelopmentalDynamic

The #spinalcord sends motor commands and relays #sensory information between the #brain and body. A new #gene expression screen in #zebrafish identified novel #transcription factors and #regulatory networks of #neural #circuitry and spinal cord function. doi.org/10.1002/dvdy.7…

The Art of Science - Cover of Developmental Dynamics Isl1/2+ ganglion and amacrine cells (green) and Caspase-3+ (red) in the developing retina and eye lid junction. With thanks to Leif Carlsson, Christoffer Nord, Iwan Jones, Maria Garcia-Maestre, and Anna-Carin Hägglund

Join us Wednesday February 26th, 12pm ET for the Inspiring Scientific Curiosity and Discovery webinar. Learn about "The evolution and development of cartilage and bone" from Dr Brian Eames. The webinar is free to attend. Register here: anatomy.org/ANATOMY/Meetin…

Inspiring Scientific Curiosity and Discovery is back after the break with guest speaker, @EamesLab on February 26 at noon EST. Sign up today and learn about the evolution and development of cartilage and bone: ow.ly/QL0n50UZBiC #Anatomy25 #AAA

Rapid generation of single-insertion #transgenics by #Tol2 transposition in #zebrafish. This study describes modifications to Tol2-mediated transgenesis that facilitates the generation of multiple independent single-insertion F1 transgenic lines doi.org/10.1002/dvdy.7…

#Arthropods, #annelids and #chordates all possess segments, the #evolution of which facilitated the generation of repeat #anatomical units. Learn how #segmentation in #tapeworms may have originated in the #muscular system. doi.org/10.1002/dvdy.7…

#Obesity affects nearly 1 in every 8 #humans and is a major risk factor for human #diseases. This review describes the mechanisms governing #adipose development, distribution and function, and the conversion of white into beige adipose #tissue. doi.org/10.1002/dvdy.7…

The Art of Science - Cover of Developmental Dynamics #Phalloidin-stained #musculature in the scolex and neck of the #tapeworm Hymenolepis microstoma. Thanks to Francesca Jarero, Andrew Baillie, Nick Riddiford, Jimena Montagne, Uriel Koziol and Peter Olson anatomypubs.onlinelibrary.wiley.com/toc/10970177/c…

#Polycystic ovary syndrome (#PCOS) is an #endocrine disorder of the reproductive system, which affects #fertility. Learn how gap junction channels impact #folliculogenesis, #oocyte growth and maturation in the #ovary, and how dysfunction causes PCOS doi.org/10.1002/dvdy.7…

During #embryogenesis, the #heart rate of an organism increases with ontogenetic maturation and #sinoatrial node cells are considered the #pacemaker cells. This study provides insights into the mechanisms of heart rate acceleration and design of pacemakers doi.org/10.1002/dvdy.7…

The #retina develops from a pool of retinal #progenitor cells into six #neuronal and one #glial cell type whose cell bodies are organized within three nuclear layers. Reduced #mTORC1-signaling in progenitor cells leads to retinal lamination deficits. doi.org/10.1002/dvdy.7…

Thank you to Dr Angelo Iulianella for a fantastic presentation and journey through formation of the cerebral cortex and cerebellum, highlighting different types of neuronal migration, and the importance of neuronal cytoarchitecture in brain development and neurological disorders.

Join us Today Oct 30 at 12pm ET for the next "Inspiring Scientific Curiosity and Discovery" webinar. Dr Angelo Iulianela will discuss “NEURONS ON THE MOVE: HOW NEURONAL MIGRATION SHAPES BRAIN ANATOMY DURING DEVELOPMENT” Registration is free: anatomy.org/ANATOMY/ANATOM…

#Craniofacial Development: Variants in #ALX4 have been associated with parietal foramina and frontonasal dysplasia with #alopecia in humans. Learn how Alx4 is crucial for craniofacial development, #hair growth and #regeneration doi.org/10.1002/dvdy.7…

#Blood Development: In this study, the authors generated epoa-deficient #zebrafish as a model of Diamond–Blackfan #anemia like (DBAL), which occurs in humans in association with recessive loss-of-function mutations in #EPO. doi.org/10.1002/dvdy.7…

Join us Wednesday Oct 30 at 12pm ET for the next "Inspiring Scientific Curiosity and Discovery" webinar. Dr Angelo Iulianela will discuss “NEURONS ON THE MOVE: HOW NEURONAL MIGRATION SHAPES BRAIN ANATOMY DURING DEVELOPMENT” Registration is free: anatomy.org/ANATOMY/Meetin…

Excellent trip to Wiley headquarters in Hoboken for the annual AAA journal strategy meeting. Stay turned for more exciting things to come at @AnatRecord, @AnatSciEduc, @DevelopmentalDy!

Thank you Dr. Steven Soper @stevesoperlab and Dr.@scott_matson @KUMedCenter for fantastic TRS presentations and discussion on precision medicine hosted by @ScienceStowers @DevelopmentalDy. We enjoyed hearing about the exciting tools developed by @Cbm2Medicine!

#Neural tube defects caused by #genetic or #environmental factors affect 300,000 babies per year worldwide. Learn how #Fuz is required for #neuroepithelial integrity, and persistent loss of neuroepithelial stiffness precedes #exencephaly. doi.org/10.1002/dvdy.7… @carlo_donato