Cell Reports Methods

@CellRepMethods

A new multi-disciplinary, gold #OA journal from @CellPressNews publishing cutting-edge methodological advances.

Joined November 2020

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Cell Reports Methods@CellRepMethods · Jul 8

TransTag enables simple and efficient transgene mapping in zebrafish via tagmentation dlvr.it/TLpf00

CellRepMethods's tweet card. Meng et al. develop a method called TransTag for simple and efficient mapping of Tol2-based transgenes in zebrafish. TransTag robustly identifies transgene insertion sites and offers an alignment-f...

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Cell Reports Methods@CellRepMethods · Jul 25

Genetic analyses of eight complex diseases using predicted continuous representations of disease dlvr.it/TM6v0l

CellRepMethods's tweet image. Genetic analyses of eight complex diseases using predicted continuous representations of disease dlvr.it/TM6v0l

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Cell Reports Methods@CellRepMethods · Jul 25

Recent advances and future prospects for blockchain in biomedicine dlvr.it/TM6mm4

Cell Reports Methods@CellRepMethods · Jul 25

Don’t miss @UCLA Päivi Pajukanta’s talk on cell-type level mechanisms for cardiometabolic disease in Mexicans @CellSymposia #CSPrecisionGen25. Early registration deadline today! hubs.li/Q03ybWnw0

CellRepMethods's tweet image. Don’t miss @UCLA Päivi Pajukanta’s talk on cell-type level mechanisms for cardiometabolic disease in Mexicans @CellSymposia #CSPrecisionGen25. Early registration deadline today!
hubs.li/Q03ybWnw0

Cell Reports Methods@CellRepMethods · Jul 23

Volumetric imaging and computation to explore contractile function in zebrafish hearts dlvr.it/TM4gRs

CellRepMethods's tweet card. Saberigarakani et al. introduce a technical framework that includes light-field microscopy, deconvolution-based reconstruction, deep-learning-based single-cell tracking, and an intuitive VR pipeline...

Cell Reports Methods@CellRepMethods · Jul 21

Combining panel-based and whole-transcriptome-based gene fusion detection by long-read sequencing dlvr.it/TM2YDB

CellRepMethods's tweet card. Rybacki et al. present a combined targeted and whole-transcriptome long-read sequencing strategy, with a computational pipeline to detect gene fusions in clinical cancer samples. By adapting a...

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Cell Reports Methods@CellRepMethods · Jul 18

High-throughput measurement of Drosophila feeding behavior dlvr.it/TM0Ggx

CellRepMethods's tweet card. Zheng et al. present a microplate platform combining automated tracking and protein-based quantification that enables high-throughput, single-fly feeding assays in Drosophila. FlyPlate-BCA facilita...

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Cell Reports Methods@CellRepMethods · Jul 17

An integrative assay for measuring social aversion and motivation in freely behaving mice dlvr.it/TLzGgY

CellRepMethods's tweet card. Grammer et al. present SAUSI, a behavioral assay that measures social motivation, fear, and hesitancy in freely interacting mice. Using this assay, they show that prolonged social isolation induces...

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Cell Reports Methods@CellRepMethods · Jul 16

CUT&Tag and DiBioCUT&Tag enable investigation of the AT-rich epigenome of Plasmodium falciparum from low-input samples dlvr.it/TLyDRw

CellRepMethods's tweet card. Gockel et al. present a version of the epigenomic profiling technique CUT&Tag adapted to the AT-rich genome of the deadly parasite Plasmodium falciparum. This low-input epigenomic profiling protocol...

Cell Reports Methods@CellRepMethods · Jul 15

Joint processing of long- and short-read sequencing data with deep learning improves variant calling dlvr.it/TLxJ65

CellRepMethods's tweet card. Gambardella shows that shallow short- and long-read sequencing combined with a retrained DeepVariant model improves small variant detection. This hybrid strategy offers a cost-effective alternative...

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Cell Reports Methods@CellRepMethods · Jul 15

A fluorescent STING ligand sensor for high-throughput screening of compounds that can enhance tumor immunotherapy dlvr.it/TLx9f5

CellRepMethods's tweet card. High-throughput screening of STING agonists remains challenging due to a lack of suitable tools. Sun et al. develop FiSL, a fluorescent STING ligand sensor, and discover honokiol as an orally...

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Cell Reports Methods@CellRepMethods · Jul 11

Dynamic stimulation promotes functional tissue-like organization of a 3D human lymphoid microenvironment model in vitro dlvr.it/TLsnbg

CellRepMethods's tweet card. Three-dimensional (3D) in vitro modeling is opening the doors to high-quality ex vivo systems for the study of blood cancers and their interaction with the tissue microenvironment. Barozzi et al....

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Cell Reports Methods@CellRepMethods · Jul 10

Deuterium labeling enables proteome-wide turnover kinetics analysis in cell culture dlvr.it/TLrsct

CellRepMethods's tweet card. Alamillo et al. present a D2O labeling mass spectrometry method to measure protein turnover rates that is compatible with multiple cell cultures and medium formulations. The method reveals a parsim...

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Cell Reports Methods@CellRepMethods · Jul 10

Graft-seq precisely maps RNA modifications via site-specific chemical grafting strategy dlvr.it/TLrkpH

CellRepMethods's tweet card. Li et al. present Graft-seq, a direct and enrichment-free technique for detecting RNA modifications at base resolution through chemical grafting. Graft-seq enables detection of internal and cap RNA...

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Cell Reports Methods@CellRepMethods · Jul 10

Secure an exclusive 1:1 meeting with a Cell Press editor to discuss your research. Meetings are on-site only and you must be registered to attend the symposium #CSPrecisionGen25. Limited spaces! hubs.li/Q03wgnj50 @CellSymposia

CellRepMethods's tweet image. Secure an exclusive 1:1 meeting with a Cell Press editor to discuss your research. Meetings are on-site only and you must be registered to attend the symposium #CSPrecisionGen25. Limited spaces! hubs.li/Q03wgnj50 @CellSymposia

Cell Reports Methods@CellRepMethods · Jul 8

Automated denoising of CITE-seq data with ThresholdR dlvr.it/TLpW1h

CellRepMethods's tweet card. Oliaeimotlagh et al. present ThresholdR, a method to denoise ADT expression data from CITE-seq experiments. This approach offers improved cell-type annotation and performance when compared with other...

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Cell Reports Methods@CellRepMethods · Jul 7

Self-supervised learning for generalizable particle picking in cryo-EM micrographs dlvr.it/TLnNyX

CellRepMethods's tweet card. Zamanos et al. introduce a self-supervised particle picking method for cryoelectron microscopy (cryo-EM) that overcomes the need for annotations. Leveraging masked autoencoders to learn micrograph...

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Cell Reports Methods@CellRepMethods · Jul 3

Excited to hear @GV20_tx @XshirleyLiu present her talk “AI-driven next-generation cancer biotherapeutics” @CellSymposia #CSPrecisionGen25 in #SanDiego. Don’t miss it— register here: hubs.li/Q03vpj220

CellRepMethods's tweet image. Excited to hear @GV20_tx @XshirleyLiu present her talk “AI-driven next-generation cancer biotherapeutics” @CellSymposia #CSPrecisionGen25 in #SanDiego. Don’t miss it— register here: hubs.li/Q03vpj220

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Cell Reports Methods@CellRepMethods · Jun 25

TAS-seq enables subcellular single-stranded adenosine profiling by signal peptide-assisted adenosine deamination dlvr.it/TLYhK5

CellRepMethods's tweet card. To study RNA structure in the cell, Wang et al. develop TAS-seq using the deaminase TadA-8e localized to subcellular compartments to enzymatically label single-stranded adenosine in RNA. This...

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Cell Reports Methods@CellRepMethods · Jun 23

Characterization of human CMV-specific CD8+ T cells using multi-layer single-cell omics dlvr.it/TLWX9P

CellRepMethods's tweet card. Gemünd et al. present a multi-omics single-cell workflow that leverages sequencing-based dCODE dextramers to sensitively identify rare, antigen-specific T cells. This approach enables comprehensive...

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