Cell Reports Medicine

@CellRepMed

Broad-scope #OA journal from @CellPressNews publishing cutting-edge science across the spectrum of #Translational and #ClinicalResearch | Editor: @DrSaraHam

USA, NLD, CHN, GBR, BEL

Joined October 2019

359Following

19KFollowers

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Cell Reports Medicine@CellRepMed · Jun 20

Xing et al. show BRAF/MEK inhibitors induce glioma cell plasticity, upregulating PD-L1 and suppressing T cells. Artwork depicts tumour heterogeneity as flowers, with PD-L1 as florets and T cell suppression as spent heads. Cover by Yao Lulu Xing.

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Cell Reports Medicine@CellRepMed · Jul 23

Interested in sharing your research at our Cell Symposium in LA? We're keeping the abstract submission system open for poster and short talk submissions until August 1, 2025. Submit here: hubs.li/Q03yrNxW0 @CellSymposia #CSStemCells25

CellRepMed's tweet image. Interested in sharing your research at our Cell Symposium in LA?
We're keeping the abstract submission system open for poster and short talk submissions until August 1, 2025. Submit here: hubs.li/Q03yrNxW0 @CellSymposia #CSStemCells25

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Cell Reports Medicine@CellRepMed · 1 h

Online now: Opantimirs: A class of antagonizing microRNAs that upregulate Opa1 and improve mitochondrial and disuse myopathies dlvr.it/TM7HVw

CellRepMed's tweet image. Online now: Opantimirs: A class of antagonizing microRNAs that upregulate Opa1 and improve mitochondrial and disuse myopathies dlvr.it/TM7HVw

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Cell Reports Medicine@CellRepMed · Jul 25

Online now: IgA2+ B cells and IgA2 anti-dsDNA antibodies are selectively targeted by belimumab after rituximab therapy in systemic lupus erythematosus dlvr.it/TM6PFl

CellRepMed's tweet image. Online now: IgA2+ B cells and IgA2 anti-dsDNA antibodies are selectively targeted by belimumab after rituximab therapy in systemic lupus erythematosus dlvr.it/TM6PFl

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Cell Reports Medicine@CellRepMed · Jul 24

Connect with us on LinkedIn for curated content, author interviews, and information on editors that may be visiting your city! hubs.li/Q03s2VLV0

CellRepMed's tweet image. Connect with us on LinkedIn for curated content, author interviews, and information on editors that may be visiting your city! hubs.li/Q03s2VLV0

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Cell Reports Medicine@CellRepMed · Jul 24

Online now: Neolactotetraosylceramide enables urinary detection of bladder cancer dlvr.it/TM5JFL

CellRepMed's tweet card. Moreira et al. show that the glycosphingolipid nLc4 is increased in bladder cancer tissue and patients’ urine. nLc4 is selectively expressed in tumor cells and secreted via extracellular vesicles....

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Cell Reports Medicine@CellRepMed · Jul 23

Online now: Recreating pathophysiology of CLN2 disease and demonstrating reversion by TPP1 gene therapy in hiPSC-derived retinal organoids and retina-on-chip dlvr.it/TM4f58

CellRepMed's tweet card. Corti et al. leverage patient hiPSC-derived retinal organoids and retina-on-chip systems to replicate key CLN2 retinal pathologies, including lipofuscin accumulation and cone dysfunction. AAV9-medi...

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Cell Reports Medicine@CellRepMed · Jul 23

Online now: Deep learning for detection and diagnosis of intrathoracic lymphadenopathy from endobronchial ultrasound multimodal videos: A multi-center study dlvr.it/TM4Knd

CellRepMed's tweet card. Chen et al. develop AI-CEMA, a deep learning system for CP-EBUS multimodal video analysis that automatically selects representative images, identifies lymph nodes, and demonstrates expert-level...

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Cell Reports Medicine@CellRepMed · Jul 22

Online now: TME-guided deep learning predicts chemotherapy and immunotherapy response in gastric cancer with attention-enhanced residual Swin Transformer dlvr.it/TM3Ycn

CellRepMed's tweet card. Sang et al. develop a multitask deep learning model, the residual Swin Transformer network, from radiographic image and clinical data, which allows non-invasive evaluation of adjuvant chemotherapy...

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Cell Reports Medicine@CellRepMed · Jul 22

Online now: Phosphoglycerate kinase 1 contributes to diabetic kidney disease through enzyme-dependent and independent manners dlvr.it/TM3GSy

CellRepMed's tweet card. Sun et al. identify PGK1 as a key metabolic driver of diabetic kidney disease (DKD). PGK1 promotes inflammation via both enzymatic and non-enzymatic mechanisms. Targeting PGK1 with small-molecule...

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Cell Reports Medicine@CellRepMed · Jul 21

Online now: CAR-T cell therapy and reconstructive oncologic surgery in peripheral solid tumors—A narrative review dlvr.it/TM2WyY

CellRepMed's tweet card. In this review, Knoedler et al. highlight the potential of integrating CAR-T cell therapy with reconstructive surgery for peripheral solid tumors. Combining advanced cellular immunotherapy with...

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Cell Reports Medicine@CellRepMed · Jul 21

Online now: Moving cellular therapies to the front line for Ph+ B cell acute lymphoblastic leukemia dlvr.it/TM2BDJ

CellRepMed's tweet card. Chemotherapy-free regimens have gained increasing attention as frontline treatments for B cell acute lymphoblastic leukemia (B-ALL) due to the limitations of chemotherapy. Zhang and colleagues...

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Cell Reports Medicine@CellRepMed · Jul 20

Online now: The expanding benefits of GLP-1 medicines dlvr.it/TM1bW0

CellRepMed's tweet card. GLP-1 medicines, initially developed for blood glucose and weight control, improve outcomes in people with cardiovascular, kidney, liver, arthritis, and sleep apnea disorders, actions mediated in...

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Cell Reports Medicine@CellRepMed · Jul 20

Online now: Intrinsic chicory root fibers modulate colonic microbial butyrate-producing pathways and improve insulin sensitivity in individuals with obesity dlvr.it/TM1PJV

CellRepMed's tweet card. Omary et al. show that 12-week supplementation with intrinsic chicory root fiber improves insulin sensitivity and cardiometabolic health. These benefits are accompanied by a functional shift toward a...

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Cell Reports Medicine@CellRepMed · Jul 19

Online now: Metabolic fingerprinting enables rapid, label-free histopathology in gastric cancer diagnosis and prognostic prediction dlvr.it/TM0zG5

CellRepMed's tweet card. Teng et al. develop a rapid and label-free histopathological method based on metabolic fingerprinting of FFPE tissue using nanoparticle-enhanced LDI-MS. The efficient method enables diagnosis,...

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Cell Reports Medicine@CellRepMed · Jul 19

Online now: RANKL/PD-1 dual blockade demonstrates survival benefit for patients with advanced lung adenocarcinoma harboring KRAS mutations dlvr.it/TM0lx5

CellRepMed's tweet card. Li et al. find that KRAS-mutant LUAD resists immunotherapy due to RANKL-driven immunosuppression via PD-L1/CXCL9-11 downregulation and reduces CD8+ T cells. RANKL inhibition combined with PD-1...

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Cell Reports Medicine@CellRepMed · Jul 18

Online now: Ce6 derivative photodynamic therapy triggers PANoptosis and enhances antitumor immunity with LAG3 blockade in cutaneous squamous cell carcinoma dlvr.it/TLzw3c

CellRepMed's tweet card. Chen et al. develop a chlorin e6 derivative-mediated PDT combined with immunotherapy, incorporating PDT, a STING agonist, and anti-LAG3. This approach optimizes the tumor immune microenvironment by...

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Cell Reports Medicine@CellRepMed · Jul 17

Online now: Endoscopic healing in pediatric IBD perpetuates a persistent signature defined by Th17 cells with molecular and microbial drivers of disease dlvr.it/TLyrQZ

CellRepMed's tweet card. Persistent inflammation compromises long-lasting remission in patients with inflammatory bowel disease (IBD). Siebert et al. identify a transcriptomic signature of residual disease in intestinal...

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Cell Reports Medicine@CellRepMed · Jul 17

Final call: Abstracts for Gene and cell-based therapies are due tomorrow Friday, July 18. Submit now for a chance to present your work at this symposium in LA! @CellSymposia #CSStemCells2025 hubs.li/Q03xfz390

CellRepMed's tweet image. Final call: Abstracts for Gene and cell-based therapies are due tomorrow Friday, July 18. Submit now for a chance to present your work at this symposium in LA! @CellSymposia #CSStemCells2025
hubs.li/Q03xfz390

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Cell Reports Medicine@CellRepMed · Jul 16

Online now: A Rac-specific competitive inhibitor of guanine nucleotide binding reduces metastasis in triple-negative breast cancer dlvr.it/TLyCDP

CellRepMed's tweet card. Dilasser et al. identified A41 as a specific RAC inhibitor. Chronic administration of A41 exhibits anti-metastatic effects in experimental models of invasive cancers (breast and colorectal cancers),...

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Cell Reports Medicine@CellRepMed · Jul 16

Online now: Perioperative administration of CBM588 in colorectal cancer radical surgery: A single-center, randomized controlled trial dlvr.it/TLxvTK

CellRepMed's tweet card. Yang et al. conduct a phase 4, open-label, randomized controlled trial and report effects of perioperative administration of CBM588 in patients undergoing colorectal cancer radical surgery. CBM588...

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