CTCPR Trials & CIRL
@CTCPR_
Center for Translational Cardiology and Pragmatic Randomized Trials / Cardiovascular Non-Invasive Imaging Research Laboratory. Led by Prof @TorBiering
We are hiring at @CTCPR_ 👇 Come join the most innovative and creative team, and help us in redefining how we should conduct randomized controlled trials in a more efficient and inclusive way. Se dette job hos Herlev og Gentofte Hospital: linkedin.com/jobs/view/4269…
🫀 New paper from the Copenhagen City Heart Study: In 3,792 people 👥 without CVD, ⬆️ remnant cholesterol was 🔗 to worse cardiac function-lower LVEF, impaired GLS, and reduced E/A-stronger than LDL’s effect 🤔 Read the paper: 👉 onlinelibrary.wiley.com/doi/10.1111/ec… @TorBiering @CTCPR_
New paper out 🚨! In high-risk CVD patients, higher education 📚 was linked to a 29% lower risk of cardio-pulmonary 🏥 or ☠️ , compared with low education 📚 level. 📖 read in @JAHA_AHA 👉 ahajournals.org/doi/10.1161/JA… @SheilaHegde @TorBiering @orlyvardeny #CardioTwitter
New episode of #KidneyCompass coming soon! Follow @HCPLiveNews for the latest releases of this podcast and many others!
📢📢📢 Stay tuned for @escardio this summer‼️ In a late-breaking session at #ESC2025 🇪🇸, @lucas_yxing will present the first results from an international effort 🌐@h2020affecteu — pooling individual-level #Afib screening study data from across the world 🚨🚨🚨…
Exciting new study by @JakobOeystein & colleagues at @CTCPR_ Full strain curves reveal hidden HF risk beyond peak GLS, uncovering novel deformation patterns — even in young, low-risk individuals. 🫀 Could transform early HF risk stratification! doi.org/10.1016/j.ijca…

Simple nudges, strong effects — new RCT by @niklasdj1 @CTCPR_ pub. in JAMA. Behavioral e-letters raised flu vax by up to +13.9 pp. Cost-effective, easy to implement, reduce risk of HF and boosts uptake in high-risk groups, cutting complications and costs. doi.org/10.1001/jama.2…

🚨 Interesting new editorial by @dons_maria from @CTCPR_ challenges “benign” moderate aortic stenosis! 💥LV & LA strain analysis offers sharper risk stratification to improve patient outcomes. ❤️🩹 Must read for cardiovascular researchers! doi.org/10.1093/ehjci/…

🚨 Review from @CTCPR_ in @Ugeskriftet : Anabolic steroids linked to hypertension, thrombosis, atherosclerosis & heart damage. ▪️ Increased risk of arrhythmia ▪️ More research needed ❗Essential read for researchers @fwemmer1, @TorBiering 🔗 ugeskriftet.dk/videnskab/anab…

New @CTCPR_ study: Elevated hs-troponin T in PSVT without heart disease means higher 30-day mortality. ▪️ 65%+ had raised troponin ▪️ 30-day death: 2.4% vs <0.01% ▪️ No long-term impact 🫀 Useful for early risk assessment 🔗pubmed.ncbi.nlm.nih.gov/39549773/

💉High-dose flu vaccine cut deaths & pneumonia/influenza hospitalizations vs. standard dose—regardless of CVD in DANFLU-1. 📉 All-cause hospitalization effect varied by CVD status. 🧪 By, @niklasdj1, @KiraJanstrup, @TorBiering @CTCPR_ 🔗 doi.org/10.1161/CIRCOU…

💌 Can a letter save lives? NUDGE-FLU-2 randomized 880K+ older adults to digital nudges vs. usual care. Small but meaningful boost—especially in those unvaccinated last year. Effect sustained across seasons. By @niklasdj1, @KiraJanstrup @TorBiering 🔗 doi.org/10.1038/s41591…

💉 Findings from DANFLU-1: High-dose flu vaccine (QIV-HD) may benefit CKD patients over standard dose 🔬 No effect modification by CKD status 📉 Fewer hospitalizations with QIV-HD 🧪@katjabartholdy, @niklasdj1, @KiraJanstrup & @TorBiering from @CTCPR_ 🔗 doi.org/10.1016/j.jacc…

We are hiring 👇 Come join our amazing team!
@CTCPR_ Center for Translational Cardiology and Pragmatic Randomized Trials is expanding due to new innovative trails being planned. Come and join us as our new Project Nurse. candidate.hr-manager.net/ApplicationIni…
@CTCPR_ Center for Translational Cardiology and Pragmatic Randomized Trials is expanding due to new innovative trails being planned. Come and join us as our new Project Nurse. candidate.hr-manager.net/ApplicationIni…

🫀 New findings from @CTCPR_ long-term outcomes after infant coarctation repair. 🩺 17-year follow-up shows late hypertension isn’t tied to surgery type or early arch size. 📉 Points to growth dynamics as bigger factor. 🔗 doi.org/10.1016/j.jtcv…

💥 Can ischemic heart disease (IHD) sabotage AF ablation? ⚠️ Preexisting IHD: no effect on AF recurrence but new IHD AFTER ablation triples AF relapse risk! 🧪 Study by @Espersen_C , @niklasdj1, @TorBiering from @CTCPR_ 🔗 doi.org/10.1016/j.hrth…

Thanks @LGHemkens for the positive feedback on our recently published ‘RCT within a large RCT’. We need to randomize to understand how we can improve processes in our society. The link to our ‘RCT within a RCT’ can be found 👇 jamanetwork.com/journals/jama/… @CTCPR_ @niklasdj1
Excellent meta-research: A trial within a large trial shows that consent form length impacts recruitment. Please consider too much text can exclude vulnerable groups / We need to rethink consent forms, too much information may harm. jamanetwork.com/journals/jama/…
Excellent infrastructure👏👏
Please find the most recent publication from @CTCPR_ in @JAMA_current 👇 In this randomized experiment embedded within the recruitment of the world largest flu vaccine trial (DANFLU-2 trial), we testet which invitation letter would increase the likelihood of trial participation
Please find the most recent publication from @CTCPR_ in @JAMA_current 👇 In this randomized experiment embedded within the recruitment of the world largest flu vaccine trial (DANFLU-2 trial), we testet which invitation letter would increase the likelihood of trial participation
A single-page digital recruitment letter increased clinical trial enrollment compared to longer letter formats, with no impact from color schemes. ja.ma/40ga7Wo