Clinical & Experimental Immunology
@CEIjournal
The journal of #translational #immunology 🔃 @britsocimm journal publishing high-quality & impactful research since 1966 Editor-in-Chief: Prof @Mauri_group
Karnopp et al. report that vitamin D boosts brain VDR expression and reduces antibody deposits in a neuropsychiatric lupus mouse model, supporting its role in modulating CNS autoimmunity. 🧠 bit.ly/467P5gA #immunology

Can TBK1 inhibition treat IBD? In a DSS colitis model, Hui et al. found that Amlexanox worsens inflammation, despite dampening key pro-inflammatory pathways, underscoring the complexity of immune regulation. 🔗 bit.ly/44Bp48h #IBD #ClinicalImmunology

T cell exhaustion could hold the key to infliximab resistance in pediatric IBD. Schnell et al. show that non-responders have elevated Lag-3+ CD4+ T cells, pointing to a potential biomarker for therapy failure. Read now🔗 bit.ly/4nKQCiR

Did you catch our very own Editor-in-Chief, Claudia Mauri, @Mauri_group speaking at this year’s #LIG2025? @London_immuno 🎤✨ Inspiring insights and impactful science from a true leader in the field!

How does epithelial cell diversity shape host–pathogen interactions in the gut? This open-access review explores how organoids are advancing our understanding of GI infections by modelling cellular heterogeneity. 📖 Read: bit.ly/422Z96U #Immunology

This study in shows that targeting FcγRIIB (CD32B) with antibodies boosts immune responses - not by blocking inhibition, but by engaging activating FcγRs. A novel strategy to enhance vaccines & immunotherapies. 🔗 bit.ly/4llbQ5n #Immunology #FcReceptors

Rims et al. reveal that the frequency and phenotype of citrulline-specific T cells mirror RA disease activity - offering a potential biomarker for immune monitoring in HLA-DRB1*04:04⁺ patients. 📖 bit.ly/4lddfL2 #RAresearch

New evidence connects Nck1 signalling to the generation of human Tregs via AKT-FoxO1 - potential implications for designing immune modulators that tweak Treg levels in disease settings. 📖 bit.ly/44dXsWr #ImmuneRegulation

Insightful review on T-cell integrins and their role in autoimmune & inflammatory diseases, covering structure, function, and therapeutic targeting in IBD, MS, and psoriasis. A valuable reference for current and emerging treatments. 📖 bit.ly/3F1Dcd5 #Immunology

🧴 New research reveals dysregulation in the TGF-β1/SMAD3 pathway in atopic dermatitis - with links to vitamin D deficiency and disease severity. Explore this molecular + immunohistochemical analysis, part of our #FOCIS2025 collection: 🔗 bit.ly/4l0RbmX #Immunology

Today marks the final day of #FOCIS2025! 🧬 Continue the momentum with our special CEI Virtual Issue, packed with cutting-edge research in allergy, immuno-oncology, Tregs & more. 📚 Explore the collection: bit.ly/4l2uSgr #Immunology #OpenAccess

🧬 Can regulatory T cells become dysfunctional like conventional T cells - and what does that mean for cell therapy? This review explores Treg dysfunction and its impact on adoptive immunotherapy Part of our #FOCIS2025 collection 👉 bit.ly/3Tb8fdC #Immunology

🧫 Revolutionizing immune research with organoid-based co-culture and chip systems explores how organoids + microfluidics are transforming how we study immune–epithelial interactions. Part of our #FOCIS2025 collection ➡️ bit.ly/44nOCV3 #Immunology #Organoids

Looking to complement the cutting-edge immunology being explored at #FOCIS2025? Check out the @CEIjournal Virtual Issue - a special collection of recent CEI papers spanning clinical breakthroughs and foundational mechanisms. 📖 Explore now: bit.ly/4l2uSgr
The #FOCIS2025 Annual Meeting begins today in Boston! To celebrate, we have curated a virtual issue highlighting recent advances in allergy mechanisms, immuno-oncology & more - perfectly aligned with the scientific programme. 🧬 Read here: bit.ly/4l2uSgr
Are you heading to #FOCIS2025? Read this specially curated selection of @CEIjournal research to brush up on recent findings in immuno-oncology, immune dysregulation, and more subjects that are covered by the programme: oxford.ly/4kQeUWF
June is #SclerodermaAwarenessMonth 🧬 This study shows that children with autoimmune rheumatic diseases including #scleroderma had comparable cellular responses to the COVID-19 vaccine as healthy peers, despite reduced antibody levels. 📖 bit.ly/3XSCZ61 #Immunology

What’s really happening inside the inflamed joints of kids with #JIA? This CEI study uses 37-parameter spectral flow cytometry to define the immune cell landscape - revealing site-specific adaptations & targets for therapy. 📖 bit.ly/449KF5Y

We’re here at the British Society for Immunology Midlands Regional Meeting 2025 (#BSIMidlands25)! 👋 Come chat with us about publishing in Clinical & Experimental Immunology - bridging the gap between clinical and academic immunologists in the Midlands.

Many congratulations to @ClareBryant13!
Congratulations to the winner of the 2025 BSI Outstanding Leadership Award, sponsored by @CEIjournal… Professor Clare Bryant, @ClareBryant13 !