Michele Boiani
@BoianiMichele
Reproductive biologist, group leader at Max Planck, Editor in Chief of Molecular Human Reproduction. Those posted here are my views.
This is us!!!!!!
“Early signaling pathways during in vitro culture of isolated primordial follicles” Don’t miss this interesting piece investigating the main transcriptional events and molecular factors determining follicle fate 🧫🐮 Dive into the full article 🔗👇 academic.oup.com/molehr/article…
Interested in #protein-targeted reverse genetic approaches? Chromosomal instability in early #development? #Endometriosis and endometrial stromal cells? Primordial #follicles activation? #Oocyte maturation? Placental DNA #methylation? Maternal-fetal interface? Chromosomal vs…
#ESHRE2025 has come to an end today with the usual series of fantastic sessions and talks, both in the main program and also in the pre-congress courses. I am especially proud to highlight once more the Symposium of our Journal (@MHR_ReprodSci), with its two speakers – Prof.…
In 2023, our group (Israel et al., Mol Hum Reprod @MHR_ReprodSci) showed that there is an intracellular fraction of zona pellucida protein 3 (ZP3) inside the oocyte, and this fraction is needed for zygote survival in mice. Now, Boiani et al. (ESHRE, Hum Reprod 2025) show that…
One sometimes needs a second look and different approaches to realize that not all was as it first seemed. It appears that the quintessential characteristic structure of #oocytes, the zona pellucida, has not only extracellular functions but also intracellular functions, which…
✨The #ESHRE Annual Meeting 2025 is just around the corner!! Join us at the #MHRsymposium where MHR’s Editor-in-Chief, @BoianiMichele, and Deputy Editor, Francesca Duncan @NUDuncanLab, will be hosting the session about Basic principles of ovarian function in vivo and in vitro.
#2024 MHR Early Career Innovator Award winner Dr. Olga Astapova!
🔹New FoR article online! Congrats to Dr. Olga Astapova, winner of the 2024 MHR Early Career Innovator Award. FoR spoke with her about her award-winning study ‘Paxillin regulates androgen receptor expression associated with granulosa cell focal adhesions’. focusonreproduction.eu/news-and-activ…
From today, all new submissions to Nature that are published will be accompanied by referees’ reports and author responses — to illuminate the process of producing rigorous science go.nature.com/44hKo29
It should be an absolute requirement of all @NIH grants that all journals reviews - including/especially when they lead to rejection - should be made publicly available.
From today, all new submissions to Nature that are published will be accompanied by referees’ reports and author responses — to illuminate the process of producing rigorous science go.nature.com/44hKo29
It is excellent news that the 'inventor' of the #organoids, Dr. Hans Clevers, has just been awarded in Germany. bmel.de/EN/topics/anim… It is a recognition of his merits, and he deserves it to the fullest. Without prejudice to the science of the Colleague, it is sad that the…
First successful generation of naïve marmoset ES cells and blastoids is now published in @MHR_ReprodSci ! This study aimed to establish the #marmoset (Callithrix jacchus) as a non-human #primate model for studying chromosomal instability and #aneuploidy during early development…
A new issue full of exciting content (#oocyte #endometriosis #IVM #sperm #meiosis) awaits you in @MHR_ReprodSci Enjoy! academic.oup.com/molehr/issue/3…
Majority IQ <=100 & they vote. To be great, a country needs its elite Einsteins. German scientists fleeing Hitler helped win WW2: Frisch & Peierls were the 1st to show atom bomb possible. US scientists are now world’s elite. Canada, UK, EU, etc should welcome them with open arms.
Scientists recreated in the mouse genetic traits characteristic of the extinct mammoth. Chen R et al. (2025): Multiplex-edited mice recapitulate woolly mammoth hair phenotypes. BioRxiv. DOI: 10.1101/2025.03.03.641227. As a result, these mice had longer, woolly fur, which is…
✨A new #EditorChoice article available on #MHR website!🧬🧫 Cava-Cami and colleagues have used a #biphasic in vitro maturation (IVM) system to culture #human cumulus-oocyte complexes with media supplementation of oocyte-secreted factors.
🧐For a long time, we believed that the first #2cells of mammalian #embryo were identical, both #totipotent. Recent advances have shown that this is not entirely accurate. Here, Nolte et al. explain the reasons behind this event and suggest a new model👇 academic.oup.com/molehr/article…
Proud to start 2025 with a paper just published in @MHR_ReprodSci For long time we believed that the first 2 cells of the mammalian @embryo were identical to each other (both @totipotent). This was inaccurate not to say incorrect. Now we also know why... academic.oup.com/molehr/advance…
