Isaac Bogoch
@BogochIsaac
Infectious Diseases physician and scientist, with thoughts on Infectious Diseases, Tropical Medicine, HIV Prevention, Public Health, and Global Health issues.
We're not going to '3rd dose' our way out of the pandemic just like we were never going to mask our way out. Vaccines (especially 1st & 2nd but also 3rd), masks, rapid tests, ventilation, sound policy, etc... ...each is a helpful tool providing additional/incremental benefit.
'tis the season. First identification of West Nile Virus in Toronto mosquitoes this year. cbc.ca/news/canada/to…
Ontario is now seeing a sharp drop in measles cases, with the trend beginning in early May.
Rocky Mountain Spotted Fever (RMSF) has been reported in dogs in Long Point, Ontario. RMSF is transmitted through tick bites, so humans are also at risk. This infection can be severe. Take care to protect yourself & your pets. Info from 🇨🇦 @PHAC_GC: tinyurl.com/yc2ev4h2
Rocky Mountain Spotted Fever in dogs, Long Point Ontario: update A couple more confirmed cases. A few more solid suspects. Some treated without testing so we can't confirm. Some dogs treated early because owners saw the alerts about RMSF and asked their vets about it.👍 1/n
A person in northern Arizona has died from a case of bubonic plague, local health officials say. nbcnews.com/health/health-…
Canada has recorded the highest number of measles cases since achieving measles elimination status in 1998.
Measles cases in Ontario are on the decline (since May).
An independent group of experts has reviewed all available evidence on SARS-CoV-2's origins, including lab leak & natural spillover. Uncertainty remains. Only a methodical & rigorous approach (not partisanship or premature certainty) will lead us to credible answers.
Today, WHO’s Scientific Advisory Group on the Origins of Novel Pathogens (SAGO), a group convened by WHO, released a report on the origins of SARS-CoV-2, the virus that caused the #COVID19 pandemic. For this report, SAGO reviewed peer-reviewed papers and reviews, as well as…
Loud claims are circulating that “no childhood vaccine was ever tested against placebo.” That is flat-out wrong. Here’s what the evidence actually shows. 🧵👇 1/
To our American friends seeking data-driven and independent vaccine advice, please check out Canada’s National Advisory Committee on Immunization (NACI): Evidence-based insights & expert guidance.. 🇨🇦🇨🇦🇨🇦 Link: tinyurl.com/3ejd4b73
On Monday, I took a major step towards restoring public trust in vaccines by reconstituting the Advisory Committee for Immunization Practices (ACIP). I retired the 17 current members of the committee. I’m now repopulating ACIP with the eight new members who will attend ACIP’s…
Update #1: Rolling clinical and epi updates for #mpox data from #SierraLeone. Watch for updated versions as additional data becomes available. Heartfelt thanks to our local colleagues in-country led by Dr. Jia Kangbai medrxiv.org/content/10.110…
Sad news from Ontario: "It is with deep sadness that I confirm that an infant, born prematurely and infected with measles, has tragically passed away in southwestern Ontario." -Dr. Kieren Moore, CMOH tinyurl.com/mckw73bu
An important commentary from Isaac and my colleagues at PHAC. As worried as I am about the situation in the US, I am at least assured that Canada is proactively addressing this threat. Gratitude for the evidence-driven preparedness efforts led by both PHAC and CFIA.
🇨🇦 Canada has secured 500,000 doses of an updated H5N1 (avian influenza) vaccine. Here's a Canadian perspective in @CMAJ on what this means, with colleagues from the Public Health Agency of Canada. Link: cmaj.ca/content/197/21… @PHAC_GC
🇨🇦 Canada has secured 500,000 doses of an updated H5N1 (avian influenza) vaccine. Here's a Canadian perspective in @CMAJ on what this means, with colleagues from the Public Health Agency of Canada. Link: cmaj.ca/content/197/21… @PHAC_GC
Rolling clinical and epi updates for #mpox data from #SierraLeone. Watch for updated versions as additional data becomes available. Heartfelt thanks to our local colleagues in-country led by Dr. Jia Kangbai medrxiv.org/content/10.110…
3 cases of #gonorrhea in Germany involved #resistance to the therapeutically important third-generation cephalosporins ceftriaxone and cefixime as well as high-level resistance to azithromycin. The pathogens were also resistant to ciprofloxacin and tetracycline.
#Germany reports cases of #gonorrhea with rare multidrug resistance in March 2025 #antibiotics open.substack.com/pub/outbreakne…
Forgotten but not gone: COVID rates in Canada have been low & declining for several months. However, the Omicron subvariant NB.1.1.8 has been more prevalent in SE Asia & it's likely we'll see more of that here in the near future. (Red = 2022-23; Yellow = 2023-24; Blue = 2024-25)
Our crowd-sourced spreadsheet of controlled vaccine RCTs just hit 189 trials - spanning Adenovirus to Zika & 2.1 million participants. Every row links to the primary paper. More to come... docs.google.com/spreadsheets/d… cc @BradSpellberg
The U.S. finally approved artesunate, the gold-standard malaria drug, in 2020 but its price jumped to $30,000 vs. $5 abroad. Delays, red tape, and cost now put lives at risk. It’s time to fix rare disease drug access. statnews.com/2021/06/11/una…