Biologic Models

Despite the Type 2 wild #poliovirus being declared eradicated in 2015, a vaccine-derived mutated version of the virus has reemerged in multiple countries. Explore the protein structure of the Type 2 Poliovirus #3DPrint #virology buff.ly/fel3xep

Here are two #3Dprints of a monoclonal antibody (blue) and a custom antibody (green) bound to the programmed cell death receptor PD1 (red). Work with one of our visualization scientists to create similar custom 3D printed protein models. buff.ly/lqsT0OR

StuartHameroff and Roger Penrose suggest networks of tryptophan residues are critical for consciousness. In this #3DPrint of Microtubule 3J2U, we can see how Tryptophan residues interconnect alpha and beta chains of adjacent tubulin molecules. buff.ly/BJwy7x4

Retroviral capsid proteins are conserved structurally but assemble differently. The mature #HIV capsid is described by as a 'fullerene cone' in which hexamers of the capsid are linked to form a hexagonal surface capped by a 12 capsid-protein pentamers. buff.ly/wG32YDy

This protein was created by Alphafold, which can be notoriously difficult to 3d print. Blue regions are confidently folded, yellow and orange regions have decreasing confidence. If you need help printing an alphafold protein, send us a #3DPrint request at buff.ly/u0ml0cB

I love how these hybrid models turn out. This is a 3D print of Neutralizing Nanobodies bound to the #SARS-CoV2 #Spike Glycoprotein #Omicron variant. This hybrid #3DPrint combines the ribbon interior with its volumetric surface. Sumbit a 3D print request at buff.ly/u0ml0cB

The Nuclear Pore Complex is one of the largest protein complexes. Its architecture is dynamic. Changes in envelope tension manifest conforma­tional breathing during dilation and constriction movements. Submit a 3D print request for a macromolecule like NPC buff.ly/Jw5Pa1v

The electrostatic potential of a protein visualizes the positively charged residues with Nitrogen atoms (blue), negatiively charged residues with Oxygen atoms (red), and neutral atoms (white). Submit a #3DPrint request at to create a custm protein model. buff.ly/u0ml0cB

This is a #3DPrint of an Antibody-drug conjugate #ADC. ADCs are targeted cancer therapies that combine an antibody with a cytotoxic drug. The ADC binds to cancer cells, delivering the drug directly to the tumor while minimizing damage to healthy tissue. buff.ly/KdipfJW

Biologic Models creates custom 3D printed protein models. Submit a #3Dprint request and work with our visualization scientist to create your 1-of-a-kind custom 3D-printed protein model. buff.ly/CxPQ1i0

3D printing x-ray crystallography data as a ribbon can be challenging. Submit a #3DPrint request for a ribbon model and one of our visualization scientists will determine how to best design and #3Dprint the dataset as a ribbon protein model buff.ly/3Ow6inV

A customer was touring the MIT Museum and saw our CRISPR and AAV models on display. Love having Biologic Models in museums. If you have a protein dataset you'd like to #3Dprint, send us a request at buff.ly/u0ml0cB

Here are two #3Dprints of a monoclonal antibody (blue) and a custom antibody (green) bound to the programmed cell death receptor PD1 (red). Work with one of our visualization scientists to create similar custom 3D printed protein models. buff.ly/x0fc4dE

Human Fibroblast Activation Protein Alpha is a serine protease overexpressed in cancer. This #3Dprint commemorates the accomplishments of researchers at the University of Iowa. Celebrate the work of a colleague with a 3D printed protein model buff.ly/u0ml0cB

The pyruvate dehydrogenase complex (PDHc) is a giant enzymatic assembly involved in pyruvate oxidation. The structure of PDHc has remained elusive due to sheer size, heterogeneity, and plasticity. Here, is a fully assembled 3D print of PHDc. buff.ly/M9vHXAS

3D Printed models of proteins created from x-ray crystallography data sets. Hand-held scientific models of proteins bridge the scientific gap between the digital and physical world. #3DPrint your own protein model at buff.ly/x0fc4dE

This is a #3DPrint of Adeno-associated Virus (AAV-2) 1LP3, a vector delivery system for human gene therapy. It is being used to treat diseases including hemophilia, cancer, and cystic fibrosis. buff.ly/cKPQOsv

More hybrid protein models being delivered to #Europe week. These protein models utilize a glass-like transparent surface and an opaque ribbon backbone interior to visualize structures deep inside proteins. Submit a #3Dprint request for a Hybrid model at buff.ly/u0ml0cB

As part of our SARS-CoV2 Receptor Binding Domain RBD series, this is a #3Dprint of the SARS-CoV1 RBD and used to compare against SARS-Cov2, RATG13, and the Pangolin Virus RBD Ribbon models for insights about the origins of the novel 2019 Coronavirus. buff.ly/f2csikg

Color coded blue-to-red from N-to-C Terminal, this is a #3DPrint of the LDL receptor-related protein 2 (LRP2), which function in endocytosis and implicated in diseases of the kidney and brain. Submit a 3Dprint request for a custom molecular model at buff.ly/u0ml0cB