Athi N Naganathan
@AthiNaganathan
Faculty @iitmadras | Protein folding
Our review on methods to map protein conformational heterogeneity - 'sequence-ensemble' paradigm holds even for folded proteins and the key lies in mapping the ensemble of states, and not just in predicting the structure! @DBTIndia @serbonline @iitmadras pubs.acs.org/doi/10.1021/ac…
🚀 Join us! Project Associate (computational protein folding and aggregation) @IMSc_Chennai 🗓 Aug 2025 start | 6 mo+ 💰 ₹48k/mo 🎓 BSc/MSc/BTech + GATE/NET • Fortran/C++/Python 📧 Apply by 31 Jul: [email protected] 🔗 RT! #ProteinFolding #Biophysics #HiringNow #ANRF
Desigining proteins that bind IDPs... 😍 science.org/doi/10.1126/sc…
Congratulations!
Happy to share the first pre-print from our lab. Here we show that 3D matrix adhesivity, degradability, porosity, and stiffness conjointly regulate the cellular and nuclear morphology and confinement in tunable microenvironments. biorxiv.org/content/10.110…
JRF/SRF position available in my lab (ad attached) Apply online: forms.gle/EbtDEeBUVLBU7H… Deadline: 15th July '25 Email for queries. Please repost. @ANRFIndia @chm_iiserb @iiserbhopal #NMR #Gquadruplex #DNA
A game-changer, Frank! Ensembles are the way forward. Congratulations!
BioEmu now published in @ScienceMagazine !! What is BioEmu? Check out this video: youtu.be/LStKhWcL0VE?si…
"An Evaluation of Biomolecular Energetics Learned by AlphaFold" - while main chain orientations are captured well, the side-chain positions, relative angles, and distances (H-bond, vdW etc.) are not predicted well. A lot more to 'deep learn' it appears! biorxiv.org/content/10.110…
Time’s running out! Lead generative AI research for molecular dynamics in our lab AIMLeNS. - Scale our NeurIPS/ICLR-published implicit transfer operators to revolutionize simulations. Postdoc position closes 10. July. Apply now: chalmers.se/en/about-chalm…
A must read for young scientists! A career in science requires a thick skin. embopress.org/doi/full/10.10…
Congratulations! Got to dig in to this too! Happy to see that the exponential trend holds across approaches :)
New preprint: Allostery is a widespread cause of loss-of-function variant pathogenicity by the great @liao_xiaotian biorxiv.org/content/10.110….
Many Congratulations to Sir (Prof. P. Balaram). Italian Peptide Society is deeply honored to unanimously confer the Fourth Edition of the Ernesto Scoffone Prize (2024) upon Professor Padmanabhan Balaram, in recognition of his remarkable and sustained impact on peptide science
Our new paper on engineered PET hydrolase! Joint research with researchers of Kirin Holdings and Koga-san (U. Osaka), led by Nakamura-san (Shizuoka U.)! Development and Production of Moderate-Thermophilic PET Hydrolase for PET Bottle and Fiber Recycling pubs.acs.org/doi/10.1021/ac…
I am extremely happy to share our recent article published in "Small" Our findings demonstrate that the efficiency of charge transport via bR molecules increases with the vesicle fusion temperature, a phenomenon not previously reported for protein based molecular junctions.
In press!! NMR & MD simulations reveal how non-native contacts stabilise a key transient intermediate in the lysozyme amyloid cascade. @MinkooAhn @JulianStreit3 @chris_waudby @ttwlodarski @FigueiredoAm @j_christodoulou @UnivCamPharm For CMD ❤️ advanced.onlinelibrary.wiley.com/doi/10.1002/ad…
Our new review paper is out @ JMB! 🧬 @katsu_s_minami @semeigazin @a_mond_future discuss DNA accessibility in euchromatin and heterochromatin in living cells. 📘 Free access: authors.elsevier.com/a/1lHgb54HFZNbb 🔗 Also, check our previous paper on nucleosome motion: science.org/doi/10.1126/sc…
New paper alert 📜
Check out the latest by @xabierjota and @daviddesancho in collaboration with Julia Contreras from @LCT_UMR7616 Work led by Asier Urriolabeitia @DIPCehu @ehu_kimika Resolving molecular interactions in protein folding trajectories with NCIPLOT go.shr.lc/3FDMP5W
For the general public - if you are interested in knowing what our lab @TIFR_Bio @TIFRScience is up to, do join: youtube.com/live/hzdvAg-xL… My students will explain what left-right symmetry is, why we are interested in this topic & how we are studying this problem using #zebrafish
WSAI encourages outstanding candidates with PhD Degree to apply for #PostDoctoral Fellowships. It provides monthly stipend significantly higher than a typical Institute Fellowship To Apply, click on - docs.google.com/forms/d/e/1FAI… More details can be found at wsai.iitm.ac.in/news/open-posi…