Arquivos de Neuro-Psiquiatria

⚡ A 9-year-old boy with worsening drug-resistant seizures was found to have a right frontal lesion on MRI—suggestive of a LEAT. Surgery confirmed angiocentric glioma (AG), a rare WHO grade 1 glioma. Early imaging clues can guide timely resection. fcj9.short.gy/fwKsng

BRAIN MRI (axial diffusion): (A–E) Multiple acute/subacute infarcts in posterior circulation — cerebellum and right mesial temporo-occipital region. (F) New vascular event in mesial right occipital lobe on follow-up. fcj9.short.gy/p3VYOE

Before Oct/22, stroke care in Piauí had no thrombolysis or stroke units. In 1 year, a telemedicine program treated 868 patients across 6 centers: 15.6% got thrombolysis (avg door-to-needle: 67min). A major step in reducing disparities in stroke care. fcj9.short.gy/EpXytg

Study shows an increase in the frequency and functional impact of levodopa-induced dyskinesia (LID) in Parkinson’s patients treated at specialized clinics in Brazil. LID remains a significant motor complication. 🔗 fcj9.short.gy/jxYOc3

Brazilian experts reached a consensus on Niemann-Pick type C, offering national guidelines for diagnosis, treatment, and follow-up—tailored to local clinical realities. A step forward for rare disease care in Brazil. #NiemannPickC Read more: fcj9.short.gy/qlrfrT

Study reveals: Increased occurrence of sexual dysfunction in female patients with multiple sclerosis evidenced by questionnaire MSISQ-19. #MultipleSclerosis #Sexuality #Autoimmunediseases #Neurodegeneration #Neurology fcj9.short.gy/SRX0lt

Arquivos de Neuro-Psiquiatria celebrates its new Impact Factor: 1.6 (up from 1.0)! This achievement reflects the journal’s growing quality and visibility. Thanks to our Associate Editors, reviewers, authors, and readers for their essential contributions! #JCR2024

MRI reveals longitudinally extensive transverse myelitis at the cervicothoracic junction, with cord swelling and a “trident-shaped” enhancing lesion—suggestive of granulomatous inflammation spreading through perivascular and meningeal lymphatics. 🔗 fcj9.short.gy/hJQUKm

A Brazilian task force developed a practical, evidence-based hospital physio protocol for stroke care — covering mobilization, positioning, shoulder pain prevention, discharge planning & more. Includes activities & quality indicators. Read more: fcj9.short.gy/fVpYoP

Neurocitoma central raro com células lipidizadas em paciente de 38 anos. Lesão intraventricular lateral com gordura intralesional — confirmada como neurocitoma grau 2 da OMS. Gordura ≠ liponeurocitoma: correlação radiológico-patológica é essencial. fcj9.short.gy/igbgKG

Meta-analysis finds no clinical benefit of GLP-1 agonists in Parkinson’s disease. No improvement in MDS-UPDRS or quality of life scores, but increased GI side effects and weight loss. Subgroup analysis confirms findings. 🔗 Read more: fcj9.short.gy/sHg6pY

STAC3 gene links congenital myopathy to malignant hyperthermia, bridging neurology and anesthesia. Early recognition and teamwork are key to prevent crises. Brazilian case series reinforces the need for vigilance. 🔗 fcj9.short.gy/iaTnx7

Is there a association between high sistolic blood pressure and amyotrophic lateral sclerosis (ALS) risk? The study uncovers a potential angiotensin-converting enzyme inhibitors for ALS treatment. fcj9.short.gy/k6FbqS

Status epilepticus (SE) is a neuro emergency: “Time is brain.” For convulsive SE, treat after 5 min (T1); damage starts at 30 min (T2). Give IV benzos, then IV ASMs (phenytoin/levetiracetam in 🇧🇷). Refractory SE may require anesthetic coma. 🔗 fcj9.short.gy/TWVPNI

NMOSD is more prevalent in Brazil, but limited access to AQP4-IgG testing delays diagnosis and care. Experts urge national guidelines, physician education, and expanded testing access to improve outcomes and reduce relapses. Read more: fcj9.short.gy/b4pLxs

🧠💬Donanemab, recently approved worldwide, was authorized by ANVISA on April 17. Experts discuss PROS, CONS, and future use of this anti-amyloid therapy for Alzheimer’s in Brazil. ✅ fcj9.short.gy/xZQycs ❌ fcj9.short.gy/5tWu06 ⚖️ fcj9.short.gy/O92ebO

Professor Horácio Canelas played a key role in Wilson’s disease research in Brazil. His work at USP’s Neurologic Clinic put the country on the international map, making it a leading center in neurodegenerative diseases with metal accumulation. fcj9.short.gy/j8ve8n

🔎 In refractory occipital neuralgia, ultrasound-guided CRFA of the proximal greater occipital nerve led to lasting pain relief in most patients—66% maintained >50% pain reduction at 1 year. Attack frequency & pain type predicted outcomes. Read more: fcj9.short.gy/FQiDRo

In low-income patients with temporal lobe epilepsy, QOL is shaped by more than seizures. Memory issues, anxiety, and depression worsen it—while social support, self-esteem, and cognition improve it. Holistic care matters. fcj9.short.gy/Pi4O5l

Brain magnetic resonance imaging showed a T2/fluidattenuated inversion recovery brainstem lesion at the dorsal pontomesencephalic junction (white arrows) with contrast enhancement (yellow arrows). Read more: fcj9.short.gy/cvbkqg