Ahmed M. Moustafa
@Ahmed_Microbes
PhD BPharm Assistant Professor @Penn & @ChildrensPhila Director Sequencing Core @PCMicrobiome Co-Director Center for Microbial Medicine
Join us at CHOP! Work alongside Drs @joeyzacks , @pauljplanet and myself. Be at the forefront of innovation with our newly launched Center of Emphasis—the Center for Microbial Medicine. careers.chop.edu/xxWP6tN
Exciting new work coming out of the Center for Microbial Medicine at @ChildrensPhila @CHOP_Research!! Development of an mRNA Vaccine for C. difficile!
Delighted to share our work developing an mRNA vaccine for C. difficile, published today in @ScienceMagazine. This study with @WeissmanLab was co-led by two truly amazing scientists: @_alexafluor from the Zackular lab and @MgAlameh (now at @CHOP_Research)! science.org/doi/10.1126/sc…
Check out this great new work by @_alexafluor in the @joeyzacks lab! Also congrats to @MgAlameh who co-led this great work. It was a pleasure to be part of this work for developing a multivalent mRNA vaccine for C. difficile.
Delighted to share our work developing an mRNA vaccine for C. difficile, published today in @ScienceMagazine. This study with @WeissmanLab was co-led by two truly amazing scientists: @_alexafluor from the Zackular lab and @MgAlameh (now at @CHOP_Research)! science.org/doi/10.1126/sc…
Delighted to announce the @KeystoneSymp meeting: Beyond #Antibiotics: Emerging Strategies Combating #BacterialInfection. Join us in Breckenridge in May 2026!! You can check out the program and amazing lineup of speakers below: keysym.us/KSAntibiotics26 #KSAntibiotics26
📢 You are invited to contribute to STREAMS: a set of community-consensus reporting guidelines for environmental microbiome studies! Read more about our workshop: zenodo.org/records/138296… and provide feedback by 10/14: docs.google.com/forms/d/e/1FAI… Reach out to us for more information!
Researchers have developed an mRNA vaccine that protected mice from succumbing to C. diff infections and prevented recurring cases. fiercebiotech.com/research/flexi…
I’m proud to share our recent publication describing the development of a multivalent mRNA-LNP vaccine for C. difficile that incorporates targets across C. diff’s complex life cycle science.org/doi/10.1126/sc…
Last week joined our colleagues & great speakers in the #MENAMicrobiome conference @SidraMedicine. We had a great panel discussion about fostering Microbiome collab. in the MENA region.Also presented our Hospital Microbiome Cartography work in the @CenterMicroMed & @CHOP_Research


The Center for Microbial Medicine will move to the new Morgan Center for Research and Innovation (research.chop.edu/about/location…) in late 2025! The building is going up quick! @CHOP_Research
Excited about our new @CAMBUpenn Microbiology, Virology, & Parasitology (aka MVP) Graduate Program t-shirts! Thanks so much Priyanka @chattergenius for the microbe-tastic design! 🦠
Thrilled to be part of the launch of the Center for Microbial Medicine @CHOP_Research! Excited to work alongside @joeyzacks, @pauljplanet and Bob Baldassano to bring microbiome-based medicine to patients and advance pediatric health. Looking forward to the amazing work ahead!
Excited to announce the launch of the Center for Microbial Medicine @CHOP_Research! This new translational Center of Emphasis at CHOP will be dedicated to finding cures and improving pediatric health through the lens of the microbiome research.chop.edu/cornerstone-bl…
After 15 a research and development, so happy to have first patients in to test phage lysine HY133 against nasal MRSA. @DZIF_ @CoE_CMFI
Eliminierung von #Staphylococcus aureus im Nasenmikrobiom: Die klinische Studie zu Phagenlysin-Wirkstoff HY-133 geht an Start: dzif.de/de/phagenlysin… #Infektionsforschung #AMR #Resistenzen
I am excited to win a CZI EOSS grant! This is the first grant I have ever won after 20+ years in science. It feels wonderful to finally be funded for my open-source contributions. With @wytamma we will deliver the next generation of my popular Snippy software! 🦘🦘🦘
Open source tools are crucial for biomedical research. We're collaborating with @KavliFoundation + @Wellcometrust to support developers & maintainers of critical #OpenSource projects, promoting innovation & community engagement in the field. More ▶️ czi.co/3zjN56l
Happy #microbiome day! The paper for our Unassigner software is published. You can now find compatible list of species for your 16S sequences using our new method. Give it a try! journals.asm.org/doi/10.1128/ms…
Come and work with us! The Bioinformatician in the PennCHOP Microbiome Program (PCMP) will develop and apply bioinformatic methods for analysis of large sequence-based microbiome data sets wd1.myworkdaysite.com/en-US/careers-…
V happy to see this out - reprocessing 5million SARS-CoV-2 genomes to remove systematic errors (+thereby improve the phylogeny) and improve representation of genomes from the Global South. Huge amount of work esp. from Martin Hunt, Angie Hinrich+collabs biorxiv.org/content/10.110…
Last week Stephanie Higgins, a lead technician in the CHOP Microbiome Center defended her Master's thesis "The effect of reagent ratio and miniaturization on library prep for shotgun metagenomic sequencing of microbiome samples" under the supervision of Drs Moustafa and Bittinger
Celebrating Ashley’s NSF GRFP with the team!!
Congratulations to amazing Zackular lab @CAMBUpenn @pennbgs graduate student, Ashley Weiss, for being awarded the NSF GRFP!! We are so proud!! @PennMicro @CHOP_Research
Excited to announce that the Microbiocode web site is now live! The site provides numerous software tools for scientific computation in Microbiome and Microbial Genomics research. Check it out! med.upenn.edu/microbiocode/
Congrats on a beautiful article by @cellseywoodruff in our lab - out today in @Nature. Organize your –80 °C freezer to save time and prevent frozen fingertips nature.com/articles/d4158… New @organizolife freezer inventory template just dropped: organizolife.com/downloads #TheLabEdit