ASCPT Journal Family
@ASCPTjournals
ASCPT is proud to publish 3 peer-reviewed scientific research journals, spanning clin pharm, pharmacometrics & systems pharmacology, and translational medicine.
🚀 New on the CTS blog: the Protocol Quality Rating Tool (PQRT) 🧪📑 a FREE way to score clinical trial protocols (comprehensiveness, organization, consistency). Use it, tweak it, share it! 🔗 bit.ly/40AdTKy #CTSjournal #ASCPTjournals
A QSP model provided confirmatory evidence during rADAMTS13's regulatory approval, supporting its benefit in reducing thrombocytopenia risk in cTTP. Read more: bit.ly/3UnFATa #PSPjournal #ASCPTjournals #ClinicalPharmacology
Struggling with PKPD model instability in drug development? This guide offers a practical, step-by-step workflow to identify and resolve modeling issues—improving stability and efficiency. Read more: bit.ly/3IC3xnf #PSPjournal #ASCPTjournals
Improving representation in clinical trials: Benedum et al. introduce POP-REFINE, a data-driven framework to evaluate and optimize trial populations, supporting more equitable and generalizable research. Learn more: bit.ly/455jVVX @ASCPT_ClinPharm #CPTJournal
How is RWE being used in regulatory review? Asano et al. share the PMDA’s perspective on using RWD as external controls in drug approval, especially for orphan diseases, and outline key considerations. Learn more: bit.ly/44iguuO @ASCPT_ClinPharm #CPTJournal #RWE
🌟 CTS Student Spotlight 🌟 Meet Nicki Kyriacou, PhD candidate @Sydney_Uni, researching how green tea 🍵 + ancestry impact cancer drug PK! 🧬 🎥 Interview + 📄 her paper now featured on @CTSJournal ➡ ascpt.onlinelibrary.wiley.com/doi/10.1111/ct…
New analysis supports the recommended maribavir dose of 400 mg BID in transplant recipients with Maribavir's anti-cytomegalovirus. Read more: bit.ly/44pIBbx #PSPjournal #ASCPTjournals #ClinicalPharmacology
Population PK analysis of rimegepant supports no dose adjustment across race/ethnicity, renal function, or formulation. Read more: bit.ly/44RP5A3 #PSPjournal #ASCPTjournals #ClinicalPharmacology
📢 #PaperOfTheMonth – July in @CTS_Journal A must-read from the BLOODPAC Consortium: 🔗 doi.org/10.1111/cts.70… 🧬 A common lexicon for #ctDNA and #MRD in solid tumors is here — and it’s a game changer for trials & regulatory clarity. 🎥 Check the explainer video below ⬇️
New study shows that CA-125 kinetics (KELIM-B) alone remains a strong predictor of PFS/OS in advanced ovarian cancer. Adding tumor size offers no added prognostic value—supporting simpler, effective predictive strategies. Read more: bit.ly/406mzIg #PSPjournal
Escitalopram dosing in the elderly: Jang et al. combine PBPK modeling and clinical data to show CYP2C19 poor metabolizers have higher drug exposure, supporting genotype-informed dosing in geriatric patients. Learn more: bit.ly/3G8mtJv @ASCPT_ClinPharm #CPTJournal
⌚ Can smartwatches improve health awareness in clinical trials? Only if people wear them! New @CTSJournal article by Arjun P. Athreya dives into adherence & engagement with DHTs in a year-long wellness study. 📄 Read here: bit.ly/4ehYRP1 #CTSjournal #ASCPTjournals
What causes bilirubin elevation with atazanavir? Dong et al. use PBPK modeling to show that OATP1B1 and OATP1B3 inhibition plays a larger role than UGT1A1. Results challenge prior assumptions and clarify biomarker limitations. Learn more: bit.ly/3GeGOwy @ASCPT_ClinPharm
New study! A multiscale QSP model links mRNA vaccine design to immune responses — paving the way for faster, smarter vaccine development. Read more: bit.ly/44s9pI1
Novel PBPK model developed by Yali Wu et al. for Furmonertinib (3rd generation EGFR TKI) & its active metabolite AST5902 enables prediction of complex chronic CYP3A4-mediated DDIs under auto-induction: bit.ly/3GcmxI3 #PSPjournal #ASCPTjournals #ClinicalPharmacology
PSP Call for Papers: Applications and Innovations in Model-Based Meta-Analysis (MBMA) Submit your work by July 31: bit.ly/4gCTOJa #PSPjournal #ASCPTjournals #ClinicalPharmacology
Check out this new #moa paper to learn more about Molnupiravir, an oral prodrug of the antiviral ribonucleoside analog, used to combat SARS-CoV-2. #CTS #ASCPTjournalfamily #MOA
📬 Call for Papers now open for the May 2026 issue of CPT: Elevating the Global Impact of Clinical Pharmacology. Hear incoming CPT Editor in Chief Karen Rowland Yeo reflect on her journey from South Africa and share her vision for the journal: bit.ly/43X7Bqu
🌟 Student/Trainee Highlight – Meet Yoonjin Kim! 🌟 #CTS #ASCPTjournalfamily #womeninmedicine
Are negative trials getting published more often? Laviolle et al. find a rise from 2000 to 2020—but no clear trend over time. Industry-funded studies still lag. Trial registration alone may not fix publication bias. Learn more: bit.ly/4e66LLf @ASCPT_ClinPharm #CPTJournal