Martinez Arias lab
@AMA_lab
Stembryo Engineering lab @upfbarcelona @the_prbb Development, cell fate decisions and #gastruloids Tweets by members of the lab
Since it's never too late, the Martinez Arias lab wishes you all a Happy New Year! 🎊
Really interesting stuff. Good to see #gastruloids increasingly put good uses. Looks as if there might be insights here as to the well noted impact of the initial PSC state in cell fate choices and differentiation.
“Lineage recording in monoclonal gastruloids reveals heritable modes of early development” Great work @JShendure @_Choi_Junhong @SRegalad0 !!!! biorxiv.org/content/10.110…
President of @ERC_Research @mleptin urge us to develope attractive academic career paths on the national level. Not everything can be solved at the EU level, prof. Letin says #Yerun10
Are you passionate about neuroscience and developmental biology? 🧠🐟 Join an exciting project on neural development in zebrafish with Gonzalo, an amazing and supportive mentor, can’t recommend him enough! #Neuroscience #Zebrafish #DevelopmentalBiology #PhDposition #PRBB #UPF
The newest version of our recent preprint is out now!
We've just updated our manuscript to a more 'publishable' version! biorxiv.org/content/10.110… New details about the role of Wnt in suppressing neural differentiation and fostering a posterior epiblast state, and the temporal effect of Nodal signalling in driving mesendodermal fates
We've just updated our manuscript to a more 'publishable' version! biorxiv.org/content/10.110… New details about the role of Wnt in suppressing neural differentiation and fostering a posterior epiblast state, and the temporal effect of Nodal signalling in driving mesendodermal fates
Here we explore the role of #Wnt and #Nodal signalling during mammalian gastrulation using #gastruloids. Building on the work of many labs, we propose that antagonistic signalling-dependent #modularity in the PS establishes the early mammalian body plan. biorxiv.org/content/10.110…
Just published a new edition of “Principles of Development’ from “Wolpert’s Principles of Development’ to honour his memory and the origin of this textbooks that aims at distilling the, sometimes elusive, principles underlying animal and plant development shorturl.at/LrOxn
We’re looking for PhD students to join the lab! 🧫🧑🔬 Curious about how metabolic processes shape patterning and morphogenesis? Enthusiastic about stem cell models for human development? - Then apply through the VBC PhD program! training.vbc.ac.at/phd-program/ ‼️Deadline: April 15‼️
Perhaps the beginning of something. #Gastruloid community, Barcelona 2025 after Marseille 2024 Nice to see human self organization at work in these challenging times. It was good to see US colleagues joining us and breathing european air! We appreciated their joining in.
Being able to bring together part of the #gastruloid community in this special meeting was incredible. Thank you all for participating in this event, and keep up the great science!
Being able to bring together part of the #gastruloid community in this special meeting was incredible. Thank you all for participating in this event, and keep up the great science!
The 2025 Gastruloid Meeting in Barcelona has already come to an end, with fascinating closing remarks by @nmoris. Many thanks to all of you for joining us and sharing your research, it was a wonderful gathering!
More fascinating talks today at the 2025 Gastruloid Meeting!
Today we kicked off the first day of the 2025 Gastruloid Meeting in Barcelona with a talk by our invited speaker @da40cambs. Thanks to all the presenters and almost 100 attendees for great discussions! Looking forward to what comes tomorrow 🙌
Amidst these troubling times, I have some positive personal news to share: I will be joining @IMBA_Vienna as a new group leader this fall! 🎉 I am excited for fun projects, surprising discoveries, and great discussions within the fantastic science community @viennabiocenter.
We are excited that former Birnstiel Award laureate @KStapornwongkul will soon join the campus upon starting her lab at @IMBA_Vienna! oeaw.ac.at/imba/research-…
🚨New preprint alert! Excited to share the latest work from our lab. In this study Ulla, Sara and colleagues investigated the role of size in #gastruloid AP patterning, tissue mechanics and elongation, with potential implications for mouse development! biorxiv.org/content/10.110…
🚨 New preprint alert! In the latest work from our lab, @_andre_Dias_ and colleagues dissected the role of a Wnt/Nodal antagonistic signalling module in patterning the emerging mammalian body plan, using #gastruloids as a model. Cool work!
Here we explore the role of #Wnt and #Nodal signalling during mammalian gastrulation using #gastruloids. Building on the work of many labs, we propose that antagonistic signalling-dependent #modularity in the PS establishes the early mammalian body plan. biorxiv.org/content/10.110…
🚨 A new preprint from our lab is out now! In this study, @JoshiFrenster and colleagues show that #gastruloids are a powerful and versatile tool to study the cellular and molecular bases of mammalian cell competition at the time of gastrulation. Nice work! biorxiv.org/content/10.110…
1/2 Early development requires fit cells. Following @MTorrescnic & T. Rodriguez, led by @JoshiFrenster we've developed a #gastruloid model #CellCompetition biorxiv.org/content/10.110… that recapitulate cell competition as in the embryo & open up experimental possibilities
For some time now we’ve been aware that Chiron #gastruloids, while representing well axial elongation, exhibit a shortage of anterior fates. Here biorxiv.org/content/10.110… led by @_andre_Dias_ we uncover the reason