Micha Fridman

@Glycoworld #glycotime article #236 Cooperatively Catalyzed Activation of Thioglycosides with Iodine and Iron(III) Trifluoromethanesulfonate mdpi.com/3413856 #mdpimolecules via @Molecules_MDPI

Excited to share our new paper published in JACS Au! "Druglike Molecular Degraders of the Oncogenic RNA-Binding Protein HuR" We report the first-in-class degraders of HuR using both molecular glue & PROTAC approaches pubs.acs.org/doi/10.1021/ja… Congrats Liann for this amazing work!

Really happy to receive the 2025 Emil Fisher Award in Carbohydrate Chemistry @eurocarb22 @BristolChem jointly with @FlitschSabine . Looking forward to the rest of the meeting.

We're happy to announce our paper about the structural elucidation of the antifungal lipopeptide AFC-BC11 from Burkholderia cepacia complex incl. insights into central steps of its biosynthesis published in @J_A_C_S ! Congratulations, @leizhong94 🥳 pubs.acs.org/doi/full/10.10…

Controlling the Helicity and Handedness of Polyaromatics with Isobenzofuranophane -Angewandte Chemie International Edition - Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/an…

🎊It has been a long and tough journey💪, but the paper is finally out online. Excited to share this work led by my first PhD student, Chenyu elucidating the structures and functions of natural bacteria-derived PGNs in the host gut. doi.org/10.1038/s41467…

Prof. Jin-Quan Yu (@YulabJin) will receive the 5th Akira Suzuki Award for his research on C–H bond activation, which makes it easier to build complex molecules. His work accelerates advances in pharmaceuticals, molecular tools and materials science. More: ow.ly/z0BL50WhOQf

Check out our recent collaborative work with Raymo and Sortino groups on discovering green-light activatable BODIPYs for super-resolution imaging of live cells: Photoactivation of BODIPY Fluorescence with Green Light | The Journal of Organic Chemistry pubs.acs.org/doi/abs/10.102…

Check out our latest publication highlighting our work with a common aspartic acid-based catalytic platform for the selective oxidation of varying functional groups! pubs.acs.org/doi/full/10.10…

Half off all carbohydrates are in the ocean ! These sugars hold tremendous potential as materials, medications and to build better climate models. Exploring marine glycans: structure, function, and the frontier of chemical synthesis - pubs.rsc.org/en/content/art…

🎊Happy to share two recent papers from the lab：Lanxin’s review on chemical biology tools for anti-fungal strategies doi.org/10.1016/j.cbpa…, and Jeric’s work on characterizing Bifidobacteria Mep on peptidoglycan modification doi.org/10.1039/D5CB00…

The Stereoselectivity of Neighboring Group-Directed Glycosylation Is Concentration-Dependent | Journal of the American Chemical Society pubs.acs.org/doi/10.1021/ja…

Our work identifying new covalent inhibitors of Staphylococcus aureus serine hydrolyses from fragment libraries is out! great work by @tulsiupadhyay.bsky.social and our many collaborators, including @christianslentz.bsky.social, @mfellnerlab.bsky.social. link.springer.com/article/10.103…

Great to see this work now available online: Cu(I)-Catalyzed Stereoselective Glycosylation of “Electron-Deficient” Glycals | The Journal of Organic Chemistry pubs.acs.org/doi/10.1021/ac… Well done @MukulMahanti @NatalieFey_NLS N. Walker and C. Sauders @BristolChem @BCS_CDT

New preprint: Ultra-sensitive, sequencing-free detection of #LungCancer via new methylation microarrays. We show >90% sensitivity & specificity from just a blood draw, with therapy monitoring potential at low-cost #LiquidBiopsy #Epigenetics #cfDNA doi.org/10.1101/2025.0…

Honored to be named a 2025 Ross M. Brown Investigator! browninstitute.caltech.edu We’re taking on a grand challenge: building stable, neutral allotropes of nitrogen (N₄) as clean, ultra energy-dense fuels. No combustion & emissions. Just on-demand decomposition to pure hot N₂ gas.

Our latest paper is now out in @J_A_C_S ! We unveil a new strategy to access elusive free oxoboranes—highly reactive species—via bridged boranoanthracenes and aromatization-driven extrusion. Congratulations to the team! pubs.acs.org/doi/10.1021/ja…

Our new preprint introduces a new approach for controlling the helicity and handedness of polyaromatics using a helical synthon: isobenzofuranophane. We demonstrate the applicability by remotely controlling the handedness and pitch of [5]helicenes. go.shr.lc/44yCyln

The First Caspase-3 Chemiluminescent Probe. Appearing today in Bioconjugate Chemistry: pubs.acs.org/doi/full/10.10…

This @glycoworld paper #234 describes a new avenue for the activation of thioglycosides. Halophilic Metal Salts for the Cooperatively Catalyzed Activation of Thioglycosides | The Journal of Organic Chemistry pubs.acs.org/doi/full/10.10…